/ Hiring

Research Associate/Sr. Research Associate - DMPK

Who We Are

At the Roche Group, about 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 30 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. The headquarters for Roche pharmaceutical operations in the United States, Genentech has multiple therapies on the market for cancer and other serious illnesses. Please take this opportunity to learn about Genentech, where we believe that our employees are our most important asset and are dedicated to remaining a great place to work.

The Position

The DMPK group is dedicated to enabling the discovery,development and commercialization of safe and effective medicines by elucidatingthe absorption, distribution, metabolism, excretion and pharmacokineticproperties of small molecule drug candidates. We accomplish this through theapplication of state of the art technologies and sciences of bioanalysis, drugmetabolism, drug transport and pharmacokinetics. The DMPK group works in closepartnership with disciplines such as medicinal chemistry, pharmacology,toxicology, pharmaceutical sciences, clinical pharmacology and regulatory tooptimize leads, select clinical candidates, conduct preclinical developmentstudies, support clinical evaluation and contribute to IND and NDA filings.

We are seeking a Senior ResearchAssociate/Research Associate to support Small Molecule Drug Discovery in theDrug Metabolism and Pharmacokinetics (DMPK) department.  The qualified candidate will work closely withour established team performing metabolic stability assays using hepatocytesisolated from various species, protein binding experiments in plasma, tissues,and microsomes from various species, and hypothesis-based in vitro metabolismassays to address specific mechanistic questions in drug discovery.  This person will perform weekly, fullyautomated, high-throughput, and high-capacity in vitro experiments to supportsmall molecule projects.  This personwill develop analytical methods (LC and MS/MS) to separate and detect smallmolecules and also proficient in using and troubleshooting LC-MS/MS.

Who You Are

B.S./M.S. in Biological Sciences/Chemistry orrelated field with minimum of 3 years of working experience (Senior ResearchAssociate will require significant amount of experience).  Experience with in vitro ADME studies andanalytical techniques (HPLC and mass spectrometry).  Must be highly motivated, organized with excellentcommunication skills (both oral and written), detail oriented, and a good teamplayer.  Experience with automation andliquid handling systems are required.

The next step is yours. To apply today, click on the "Apply online" button below.

Genentech is an Equal Opportunity Employer.