The Senior Clinical Coordinator, Franchise Sales bringsclinical knowledge and expertise to the assigned franchise sales team.  The Senior Clinical Coordinator helpsclinical specialists and their customers increase their knowledge andunderstanding of the assigned GNE brand(s); their benefits and use as thesepertain to the relevant therapeutic area/disease state and approvedindication(s).

 

Reports to: Clinical Coordinator Field Manager

 

Example Duties andResponsibilities:

*Participates in territory/division/regional businessplanning

*Recommends opportunities to increase account knowledge ofGNE brand(s)

*May provide input into marketing materials

*Actively participates in local clinician groups

*Provides training and education sessions regarding GNEbrand(s) and their approved indication(s). Uses approved training/education materials

*Supports clinical specialists in other ways/means byattending periodic account meetings; helping to further increase accountknowledge of GNE brand(s)

*Complies with all laws, regulations and policies thatgovern the conduct of GNE activities

*Business travel, by air or car, is regularlyrequired 
...

Responsibilities:  A postdoctoral position is available to study oncogenic pathways in breast cancer.  Strong molecular and cellular biology skills are required. The successful candidate should have familiarity with mutagenesis, RNAi, signal transduction, and protein characterization. Candidates with a strong background in protein structure and function will also be considered. A practical working knowledge of bioinformatics analysis would be desirable.  The successful candidate will be required to work in a highly collaborative and multi-disciplinary environment. See recent publications: Cancer Cell 20:472 (2011); Cancer Cell 15:429 (2009); Cancer Res 68:9280 (2008).

...

The Department is currently seeking an additional Pathologist to work with five of its Pathologists to help them support (i) research scientists who discover and develop drugs for the treatment of cancer, and (ii) research scientists and clinicians who discover and develop biomarkers for pharmacodynamics and patient selection purposes in Phase I, II and III clinical trials of oncology therapeutics.

The successful candidate will be familiar with, if not expert in, the molecular, cellular, systems biology, and pathogenic mechanisms of cancer. He/she will have a strong interest in providing pathology support for drug and biomarker discovery programs in cancer, and an appreciation for the need for potential flexibility in contributing support to programs outside of oncology as the need arises.  Depending on the candidate and the availability of resources, there may be an opportunity for the individual to spend part of his or her efforts in basic and/or translational research activities that have relevance to the company’s business goals.

...

We are seeking candidates for a postdoctoral fellow position in the Ashkenazi lab to study the molecular mechanisms that control apoptosis activation in response to cell stress. 

...

Lab: Bob Lazarus
http://www.gene.com/scientists/our-scientists/bob-lazarus

Responsibilities:
A postdoctoral position is available in the Department of Early Discovery Biochemistry to investigate biochemical aspects of protein/protein and protein/ligand structure function relationships.  Areas of interest include proteases and pseudoproteases, molecular basis of protein/protein interactions, protein scaffolds, phage display technology and will involve collaborative interactions in a multidisciplinary group.  Specific projects include ongoing aspects of HGF/Met signaling, zymogen activation, new targets in pathways of cancer biology, neurobiology, immunology and infectious disease.
...

We have an opening for a talented electrophysiologist to join our Biochemical and Cellular Pharmacology group as part of the small molecule drug discovery program in our South San Francisco location.

Responsibilities:

• Provide support for specific projects in the neuroscience and immunology indications using in vitro electrophysiological techniques as well as standard medium and high-throughput biochemical and cell-based assay technologies.
• Develop, optimize and validate protocols for ligand and voltage-gated ion channel targets to execute ultra-high throughput screening campaigns and evaluate the structure-activity relationships (SAR) and mechanism-of-action of small molecules in the context of multi-disciplinary project teams.
• Provide scientific guidance to the prosecution of ion channel small molecule targets, including assay development, assay cascades, and counterscreening strategies.
• Leadership in employment or development of new technologies, including medium throughput electrophysiology equipment
• Collaborate closely with our medicinal chemists, in vivo pharmacologists, and therapeutic area biology experts.
• Provide leadership and guidance to a focused team of direct reports, including junior PhD level scientist(s) as well as highly experienced Senior Research Associates.

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We are seeking a postdoctoral fellow to work in the laboratory of Dr. Eric Brown. The incumbent will conduct original and significant basic investigations in the area of the pathogenesis of infectious diseases and host response to infection. The expectation is that this work will result in novel and important contributions to understanding of host-pathogen interactions, as evidenced by publication in top tier scientific journals. The laboratory explores both host and pathogen genetics as its approach to understanding the host-pathogen interface and uses a wide variety of genetic, cell biologic, and biochemical methods to investigate these questions. Projects in the Brown lab currently focus on molecular mechanisms and pathologic consequences of Type VII secretion and on regulation of autophagy by ubiquilins....

Crystallography Post Doctoral Fellow - Hymowitz Lab

Responsibilities:

A position is available for a postdoctoral fellow with expertise in crystallography to join the Department of Structural Biology at Genentech, Inc.  Active areas of research include the structure and function of intracellular signaling cascades involving ubiquitin as well as the structure and function of protein complexes relevant to human disease. The successful candidate will be involved in all aspects of crystallography, including expression and purification of proteins, crystallization, data collection, structure determination and analysis of protein structures.

...

Genentech is currently searching for a Senior Director, Department of Immunology. The incumbent in this role will be responsible for all target and therapeutic discovery activities for autoimmune and inflammatory diseases in the Genentech Research and Early Discovery organization. The incumbent also will oversee the interactions between the Immunology Department and all diagnostic, clinical, commercial, and business development activities for these diseases.

...

We are seeking an energetic and accomplished Research Associate/Senior Research Associate in Early Discovery Biochemistry within Genentech.  Our group conducts early drug discovery and new target validation from a biochemical/physical, structural, and computational perspective and collaborates with diverse discovery biology areas in Genentech. The candidate must have excellent skills with directed evolution techniques, such as phage display, yeast display, and/or mRNA display. Preference will be given to candidates who also have experience in computational biology and/or biophysics. Projects will span a wide range of areas, and the candidate must be flexible, creative, and able to master new techniques as needed.
...

Responsibilities: The successful candidate will participate in the discovery and investigation of novel small molecule drug targets in the therapeutic area of immunology.
Using state of the art techniques and technologies, he/she will investigate various signaling molecules, such as kinases, transcription factors, enzymes, and epigenetic regulators, and assess their potential therapeutic utility. Furthermore, the candidate is expected to independently design, execute, analyze and present experiments to various forums within and beyond the department of discovery immunology, and thus must have excellent communication and interaction skills.
...

TheImmunology, Tissue Growth and Repair Diagnostic Discovery Department is seekinga motivated, interactive and flexible Senior Research Associate to perform researchrelated to biomarker discovery and analysis in infectious diseases. 

Theposition will report to a Scientist lead for the Department's new program inInfectious Disease and Host-Pathogen responses. The successful candidate willimplement a variety of in vitro and in vivo molecular, proteomic and cellulartechniques to elucidate disease pathways and identify relevant biomarkers, andwill be expected to make intellectual as well as technical contributions to theteam. Responsibilities: Perform wet lab experiments, generate and analyze dataand communicate findings and interpretations relevant to the Department'smission to identify predictive and prognostic biomarkers for therapeuticResearch and Development programs. Specific responsibilities will include:performing exploratory disease-oriented research utilizing samples & datafrom human infectious disease cohorts, processing and analyzing clinical trialsamples, data analysis and presentation, and contributing to experimentaldesign/planning.

...

Purpose

In partnership with senior leadership, responsible for strategic direction and execution of medical communication plans for marketed products, pipeline molecules, and therapeutic area support. Oversight for MC scientist teams. Ensures product specialist resources are positioned to support current and future company needs. Accountable for the long-range financial planning and resource management for med comm product support.  Liaison responsible for directing and influencing corporate groups to achieve shared goals and objectives.

Job Description:

• Oversight for daily operations of the MC scientist teams, including responding to unsolicited requests, creation and maintenance of document response library, support for product launches, internal team support, and responding to label changes

• Provide oversight and leadership to the management team including strategic planning and tactics aligned with corporate and product priorities, champion department goals, and brand planning

• Year over year finance and resource budget planning as well as future resource forecasting for therapeutic area

• Accountability for representing MC at multidisciplinary senior-level cross functional committees including: Label committee (LC), reprint dissemination committee (RDC), healthcare compliance committee (HCC), patient communications committee (PCC), medical communications leadership team, and other committees where relevant; safety sub-teams (SST), promotional review committees (PRCs), Medical teams, major scientific meeting taskforce teams

• Career development of future leadership and succession planning for manager teams. Empower his/her staff to make sound decisions, and delegate as appropriate

• Develop and maintain collaborations with multiple corporate partners including Roche global, Novartis, Merk-Serono, Abbott, Biogen-Idec, and OSI pharmaceuticals

• Ensuring effective and efficient cross-product and cross-activity support via senior leadership collaborations

• Maintain awareness of the present state of business and needs by maintaining relationships with all relevant areas within and external to the Medical Affairs Organization

• Interacts and represents MC department with internal customers including but not limited to: Sales, Marketing, Clinical Operations, Clinical Science, Regulatory, Legal, and Safety.  Frequently represents MC outside of department  

...

Job Description

The Senior Business Systems Analyst position will work in Medical Communications and is primarily responsible for but not limited to the following;

• Analyzes business scenarios and identifies opportunities for improvement through automation and/or business process change
• Provides analytical expertise in identifying, evaluating, designing and developing systems and procedures that are cost effective and meet user requirements
• Provides consultation to users in the area of business systems and processes
• Applies advanced technical principles, theories, and concepts related to requirements, data, usability and process analysis
• Facilitate strategic initiatives in Medical Communications/US Medical Affairs, as well as business partners across Roche/Genentech
• Conduct ongoing feasibility studies and gap-analysis for improvements through automation and/or business process changes
• Assist business function areas in understanding strategic problems, opportunities, and the big picture for the functions to make informed decisions to support the business long-term
• Propose strategic recommendations for process improvements and streamlining across the organization
• Articulate and communicate project portfolios alignment with overall business strategies to management and key stakeholders
• Assist management to report business health (success/achievements or areas requiring focus) 
• Liaise with IT to ensure accuracy and completeness in user requirements, functional requirements, technical specifications, process flow diagrams; may configure some system settings and/or options; also, partner with IT to drive implementation of technical solutions.
• Leads cross-functional analytical teams in the resolution of business or systems issues.
• Leads successful completion of major projects/programs across portfolios. Champions accountability by example

...

The candidate will be working in the design, performance and analysis of virus clearance studies, evaluating virus removal by protein recovery processes. Candidate will execute chromatography and/or filtration processes and perform Q-PCR, or cell-based, assays. Candidate will be responsible for scaled-down chromatography and filtration of the recovery process, as well as virus nucleic acid purification and quantification. Candidate will write GMP protocols, summary reports and execute validation studies. Depending on the business needs, candidate will support the development and implementation of recombinant protein purification process from laboratory to manufacturing scale.  The work may include purification process development, optimization, characterization, and validation. The work includes projects carried out at laboratory, pilot plant, and industrial scale using separation unit operations including column chromatography, filtration, and centrifugation. The successful candidate will also collaborate with many different functional groups and work on the development of state-of-the-art technology on viral clearance or protein purification.

...

Senior Health Economist (E5)/ Principal Health Economist (E5A)

RESPONSIBILITIES INCLUDE:

-Design, develop, conduct and manage HEOR studies for assigned products and indications in the cardiometabolism or neuroscience therapeutic areas

-Develop, maintain and apply in-depth knowledge of role, including disease state and clinical topics, market/ customer landscape, and emerging issues.  

-Work independently with minimal guidance, direction and mentoring from manager and others to clarify directions and expand knowledge and skills

-Proactively collaboration with various functions including medical directors, commercial, managed care marketing, development and other gMed functions to ensure alignment of activities with key partners and stakeholders

-Develop HEOR strategy for the medical plan for pre-launch and/or post-marketed products.  

-Design and execute prospective and retrospective outcomes research studies, in collaboration with academic consultants and contract research organizations.  -Develop economic models and AMCP dossier chapter to support launch. Manage budgets, timelines and deliverables as planned.

-Lead and/or participate in HEOR and cross-functional projects. 

ABILITIES:

- Demonstrate strong leadership and communication skills; can contribute to the development of vision and strategy in Medical Affairs teams.

- Demonstrate abilities to manage complex responsibilities, to include integration across multiple projects and priorities

-Strong orientation to teamwork: works collaboratively, effectively and efficiently with others in a matrix project team environment

...

All candidates are welcome to apply, but a preferred candidate has been identified.

The Senior/Principal Health Economist is part of the broader Oncology Medical Unit organization and provides health economics and outcomes research, modeling, reporting, and other relevant analyses, within applicable legal and regulatory guidelines, which can be used to quantify the value of Genentech products in economic or societal terms. 

The Senior/Principal Health Economist will work with multiple products and indications within the Oncology portfolio and will support cross-functional Genentech and Roche teams by recommending, developing/conducting and advising on HEOR research and modeling strategies, and by developing medical and payer value propositions, portions of product dossiers, and other scientifically-based communications. 

This team supports strategic decision-making for late-stage development and across the product lifecycle. The Senior/Principal Health Economist helps set Genentech HEOR strategies, direction, objectives, and plans for innovative, effective and efficient execution. 

The Senior/Principal Health Economist will be fully accountable for compliance with all laws, regulations and policies that govern the conduct of Genentech activities. As a manager and coach of others, the AD/PHE is not only accountable for his/her own compliance, but also for the compliance of all individuals in his/her team. As such, s/he leads the way and leads by example by demonstrating full knowledge and commitment to all applicable policies. The Senior/Principal Health Economist monitors adherence to company policies and guidelines and acts according to established procedures to ensure all issues are addressed and resolved as required. ¿

Responsibilities:

Incumbents are generally expected to:

• Functional lead for HEOR activities for the molecules and indications assigned, including participation in design and conduct of studies as needed

• Set and manage to outside spend budgets for multiple projects and products, including assuring that direct reports meet budget commitments and develop financial management skills

• Manage one or more health economists or other HEOR staff, with less than half of his/her time devoted to management

• Including hiring, development and ensuring technical excellence

• Directly engaged in designing, developing and conducting HEOR studies with strategic impact for the molecules for which she/he is responsible

• Maintain strong, positive relationships with senior internal stakeholders across Genentech and Roche 

• Lead development of the vision, strategic and tactical plans, resource and budget plans, for the products and indications under his/her responsibility.  Includes establishing annual and longer-range plans, goals and objectives, and effectively aligning these with Genentech and Roche cross-functional research, development and commercial strategies and objectives.

• Lead and manage execution to ensure work is completed on-time, on-target and within-budget, with the highest levels of accuracy and relevance, and in consistent compliance with legal and regulatory guidelines, Genentech and Roche policies & procedures:

• Working collaboratively, effectively and efficiently with all internal and external customers, partners, stakeholders and influencers

• Develop and cultivate relationships with key KOLs (Key Opinion Leaders) and other thought leaders, to support HEOR strategies, plans and objectives and provide strategic, critical influence for Genentech's product pipeline and portfolio

• Act, and is accountable for others in his/her team acting, in complete & total compliance with all laws, regulations and policies.

• Utilize only approved resources and messages to meet goals and targets

...

The Project Manager position will work in the Operations & Business Infrastructure function and is responsible for planning, executing, evaluating projects according to predetermined timelines & budgets, and ensuring quality control throughout project life cycles. The primary responsibilities include, but are not limited to, the following:

• Provide business and project management support across a broad range of projects in Medical Affairs with primary focus on providing support to the Field Medical Teams (FMT)
• Build and manage the FMT Strategic and Operational Plan, working with key internal stakeholders to enable effective evaluation of current gaps, future needs, prioritization and resource alignment/allocation
• Perform project budget and work plan reviews, project alignment and prioritization activities and resource utilization analyses
• Partner with IT function and/or work with project sponsor and stakeholders to complete project charter outlining scope, goals, deliverables, required resources, budget and timing
• Responsible for driving and delivering the project on-time & within budget and meeting the strategic business needs through effective project management methodology/principles
• Manage project scope, resources and stakeholders expectations/requirements
• Develop systematic approach, ongoing improvements and innovations to enhance performance in problem solving and project management
• Build coalitions among the various stakeholders and negotiate authority to move projects forward
• Proactively engage stakeholders throughout the project to gain their commitment, agreement and support on the proposed solutions, priority setting and implementation
• Consult and provide advice; facilitate discussion and resolve conflict; establish trust, build and use cross functional relationships to accomplish work objectives
• Advocate on behalf of stakeholders to negotiate with service provider (e.g. vendor and/or IT function) to ensure proper solutions meet the business strategic objectives
• Facilitate and lead all aspects of organizational changes for the assigned project responsibilities
• Communicate and/or present project timeline, risks, and overall status to the business functional leaders, senior managers, all appropriate stakeholders, and project team members
• Establish timely and proper communications to business sponsor and stakeholders that includes centralizing projects activities & information via dashboard or other mechanism
• Make decisions and take timely independent action in pursuit of priorities

...

RESPONSIBILITIES INCLUDE:

-Design, develop, conduct and manage HEOR studies for assigned products and indications in the immunology and infectious disease therapeutic areas.

-Develop, maintain and apply in-depth knowledge of role, including disease state and clinical topics, market/ customer landscape, and emerging issues.

-Work independently with minimal guidance, direction and mentoring from manager and others to clarify directions and expand knowledge and skills.

-Proactively collaborate with various functions including medical directors, commercial, managed care marketing, development and other gMed functions to ensure alignment of activities with key partners and stakeholders.

-Develop HEOR strategy for the medical plan for pre-launch and/or post-marketed products.  

-Design and execute prospective and retrospective outcomes research studies, in collaboration with academic consultants and contract research organizations.  -Develop economic models and AMCP dossier sections to support launch.

-Manage budgets, timelines and deliverables as planned.

-Lead and/or participate in HEOR and cross-functional projects. 

ABILITIES:

- Demonstrate strong leadership and communication skills; can contribute to the development of vision and strategy in Medical Affairs teams.

- Demonstrate abilities to manage complex responsibilities, to include integration across multiple projects and priorities.

-Strong orientation to teamwork: works collaboratively, effectively and efficiently with others in a matrix project team environment.

...

Purpose

To provide relevant, balanced, and timely evidence-based clinical information on Genentech products to managed care customers that make decision regarding drug coverage and reimbursement, .

Description

The Associate Scientist or Scientist for Managed Care Medical Communications (MCMC) is able to communicate relevant and timely clinical information on our marketed products and compounds in late development.  More specifically, this position is responsible for communicating effectively with external customers involved in evidence-based healthcare decisions including but not limited to managed care organizations, private and government health plans, third party payors, pharmacy benefit managers, specialty pharmacies, compendia publishers, guideline bodies and technology assessment entities.  The MCMC Associate Scientist/Scientist is expected to evaluate and interpret medical literature, abstract and write medical information in various response formats, conduct scientific and clinical presentations, and apply managed care concepts and knowledge to customize our services for managed care customers.  More specifically, an understanding of the comparative effectiveness research (CER) and health technology assessment (HTA) landscape is required, as well as the ability to review, assess and synthesize CER, health outcomes research and pharmacoeconomic evidence.  Medical information is prepared and communicated using many formats (response documents, formulary dossiers, slide presentations, compendia submissions, web-based media, scientific meetings, etc.).  This position is also involved in the review of promotional marketing materials intended for the managed markets and payor environment.  The MCMC Associate Scientist/Scientist shall effectively, appropriately, and responsibly use resources to support the use and access of our marketed products.  

The MCMC Associate Scientist/Scientist may contribute to departmental efforts to develop, implement or further improve business processes and operations.  This may include non-clinical and non-product types of responsibilities and activities such as systems and technology, training, quality assurance, writing policies and procedures.  Some business travel is expected.

Candidates should have a sound understanding of legal and regulatory topics to adequately describe the basis of Medical Communications (MC) policies and practice.  He/she must work effectively with members of the MCMC/MC staff and other internal customers that include but are not limited to: Medical Directors, Health Economics and Outcomes Research, Managed Care Liaisons, Project and Execution Managers, Regulatory, Legal, Managed Care Marketing, Field Managed Care, Medical Science Liaisons, Sales, Marketing, Access Solutions Reimbursement, and Corporate Partners.  This position shall partner with these entities to meet the information needs of managed care customers, contribute to corporate wide goals, and support the safe and effective use of Genentech products.

...