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Scientist Profile

Nik Chetwyn

Associate Director, Pharmaceutical Sciences
 
"My vision is to bring together the best and the brightest scientists to leverage Genentech's knowledge of disease with a shared and focused goal of helping others."
 

I joined Genentech in June of 2006 with the task of building a Small Molecule Analytical Chemistry group, which is an integral part of Small Molecule Pharmaceutical Sciences - along with the Pharmaceutics, Process Chemistry and Scale-Up groups.

I was excited by the opportunity to join a company known for its excellent science and track record in fighting life-threatening diseases - especially cancer. Genentech is respected for its exceptionally strong biology and knowledge of large molecule drugs, but this was a chance to be part of an exciting new direction - utilizing the excellent biological understanding of a target to develop new small molecule therapeutics. I am privileged to be part of an enthusiastic team of great scientists in a collaborative and science-driven culture dedicated to one thing: fighting human diseases.

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My Focus

My team and I are currently working on a broad range of drug candidates mainly with a focus on oncology. A large part of my current work is recruiting and building a world-class team of analytical chemists. The group is steadily growing and we have recently moved into new, state-of-the-art laboratories.

 
Publications & Recognition
  • Capillary electrophoresis in pharmaceutical analysis.
  • Pharm Res 1997 Apr; 14(4): 372-87.
  • Holland LA, Chetwyn NP, Perkins MD, Lunte SM.
  • Characterization of sulphoalkyl ether derivatives of beta-cyclodextrin by capillary electrophoresis with indirect UV detection.
  • J Pharm Biomed Anal 1992 Sep; 10(9): 615-22.
  • Tait RJ, Skanchy DJ, Thompson DP, Chetwyn NC, Dunshee DA, Rajewski RA, Stella VJ, Stobaugh JF.
  • A stability-indicating assay and the preformulation characteristics of the radiosensitizer, 1,2,4-benzotriazin-3-amine 1,4-dioxide.
  • J Pharm Biomed Anal 1993 Feb; 11(2): 131-8.
  • Riley CM, Riley CM, Chetwyn NC, Kasper VT, Kindberg CG, Dicken CM.
 
View All Publications & Recognition
 
  • The University of Kansas, Lawrence, KS.
  • Pharmaceutical Chemistry Ph.D.
  • 1997
  • The University of Kansas, Lawrence, KS.
  • Pharmaceutical Chemistry MS
  • 1994
  • University of Sunderland, Sunderland, U.K.
  • Chemical and Pharmaceutical Sciences, B.Sc.(Hons)
  • 1992
Publications & Recognition
  • Capillary electrophoresis in pharmaceutical analysis.
  • Pharm Res 1997 Apr; 14(4): 372-87.
  • Holland LA, Chetwyn NP, Perkins MD, Lunte SM.
  • Characterization of sulphoalkyl ether derivatives of beta-cyclodextrin by capillary electrophoresis with indirect UV detection.
  • J Pharm Biomed Anal 1992 Sep; 10(9): 615-22.
  • Tait RJ, Skanchy DJ, Thompson DP, Chetwyn NC, Dunshee DA, Rajewski RA, Stella VJ, Stobaugh JF.
  • A stability-indicating assay and the preformulation characteristics of the radiosensitizer, 1,2,4-benzotriazin-3-amine 1,4-dioxide.
  • J Pharm Biomed Anal 1993 Feb; 11(2): 131-8.
  • Riley CM, Riley CM, Chetwyn NC, Kasper VT, Kindberg CG, Dicken CM.
Awards & Honors
  • Pfizer Site Recognition Award
    2004
  • Procter and Gamble Graduate Fellowship
    1997
  • PhRMA Fellowship
    1995-1996
  • A.W. Davidson Outstanding Graduate Student Award
    1994
  • IAPBA Graduate Fellowship
    1993-1994
  • Glaxo Prize and Pfizer Prize: First in Class Graduation and Best Undergraduate Research Thesis
    University of Sunderland
    1992