Stock Listing Genentech is listed on the New York Stock Exchange under the symbol DNA.

Transfer Agent

Communications concerning transfer requirements, lost certificates and change of address should be directed to Genentech's transfer agent:

Annual Meeting

The annual meeting of stockholders will be held at 10:00 a.m. Pacific time on May 10, 2001, at The Westin Hotel, 1 Old Bayshore Highway, Millbrae, California. Detailed information about the meeting is contained in the Notice of Annual Meeting and Proxy Statement sent to each stockholder of record as of March 13, 2001.

Investor Relations

Genentech invites stockholders, security analysts, representatives of portfolio management firms and other interested parties to contact:

Additional Information

If you need additional assistance or information regarding the company, or would like to receive a free copy of Genentech's Form 10-K and 10-Q reports filed with the Securities and Exchange Commission, contact the Investor Relations Department at Genentech's corporate offices by sending an e-mail message to investor.relations@gene.com or calling (650) 225-1599. You can direct requests for literature to Genentech's literature request line at (800) 488-6519 or you can visit Genentech's site on the World Wide Web at www.gene.com.

Independent Auditors

Ernst & Young LLP Palo Alto, California