Boniva® (ibandronate sodium) Tablets
Full Prescribing Information (PDF)
Medication Guide (PDF)

BONIVA is a prescription medication used to treat or prevent osteoporosis in women after menopause. BONIVA helps increase bone mass and helps reduce the chance of having a spinal fracture (break).

It is not known how long Boniva works for the treatment and prevention of osteoporosis. Patients should see their doctor regularly to determine if Boniva is still right for them.

It is not known if Boniva is safe and effective in children.

Important Safety Information for Boniva Tablets

• People should not take BONIVA if they have problems with their esophagus, low blood calcium, can’t sit or stand for at least 1 hour or are allergic to BONIVA or any of its ingredients.
• BONIVA can cause serious side effects including problems with the esophagus, low blood calcium, bone, joint, or muscle pain, severe jaw bone problems, and unusual thigh bone fractures.
• The most common side effects are back pain, heartburn, stomach area pain, pain in the arms or legs, diarrhea, headache, muscle pain, and flu-like symptoms.
• Patients must stop taking BONIVA and tell their doctor if they have difficulty or painful swallowing, chest pain, or severe or continuing heartburn, as these may be signs of serious upper digestive problems. Patients must stop taking Boniva and tell their doctor if they have symptoms of low blood calcium such as spasms, twitches, or cramps in their muscles or numbness and tingling in their fingers, toes or around their mouth. Patients must tell their doctor if jaw problems or severe bone, joint, muscle, thigh and/or groin pain develop.
• Patients must follow dosing instructions carefully.
• For additional safety information, please read the full prescribing information (PDF) and medication guide (PDF)

Boniva® (ibandronate sodium) Injection
Full Prescribing Information (PDF)
Medication Guide (PDF)
Healthcare Professional Letter for new NDC number for Boniva Injection (PDF)

BONIVA is a prescription medication used to treat or prevent osteoporosis in women after menopause. BONIVA helps increase bone mass and helps reduce the chance of having a spinal fracture (break).

It is not known how long Boniva works for the treatment and prevention of osteoporosis. Patients should see their doctor regularly to determine if Boniva is still right for them.

It is not known if Boniva is safe and effective in children.

Important Safety Information for Boniva Injection

• BONIVA Injection must be administered intravenously only by a health care professional. Boniva must not be administered in any other way.
• Patients should not take Boniva if they have low blood calcium or are allergic to Boniva or any of its ingredients.
• Boniva can cause serious side effects including low calcium levels in the blood, severe kidney problems, severe jaw bone problems, bone, joint or muscle pain, and unusual thigh bone fractures.
• The most common side effects of Boniva injection are pain the bones, joints or muscles, headache, and flu-like symptoms such as fever, chills, bone, joint or muscle pain, and fatigue.
• Patients must stop taking Boniva and tell their doctor if they have symptoms of low blood calcium such as spasms, twitches, or cramps in their muscles or numbness and tingling in their fingers, toes or around their mouth. Patients must tell their doctor if jaw problems or severe bone, joint, muscle, thigh and/or groin pain develop.
• For additional safety information, please read the full prescribing information (PDF) and medication guide (PDF)