Full Prescribing Information for Nutropin AQ

Nutropin AQ® [somatropin (rDNA origin) injection] is indicated for the treatment of growth hormone deficiency in children and adults, growth failure associated with chronic renal insufficiency prior to kidney transplantation, short stature associated with Turner syndrome, and long-term treatment of idiopathic short stature.

Nutropin AQ® NuSpin™ is a prefilled, multi-dose injection device for Nutropin AQ® [somatropin (rDNA origin) injection], a recombinant growth hormone that works the same as naturally occurring growth hormone.

NuSpin 10 and 20 became available on April 28, 2010, and have several innovative features designed to provide patients with a simple way to administer growth hormone including:

• A unique sliding dose activator that delivers Nutropin AQ automatically, eliminating the need for patients to push a plunger;
• An innovative "spinning" dose knob that signals that the full dose has been delivered; and
• Prefilled 5 mg, 10 mg, and 20 mg cartridges that require no mixing, creating a simpler administration process with fewer steps and flexible dosing options.

Read more about Nutropin AQ® [somatropin (rDNA origin) injection] and Nutropin AQ Nuspin (53K/PDF)

Important Safety Information

• Nutropin is not for children and teenagers whose bones have finished growing.
• Nutropin is not for patients who have certain types of eye disease caused by diabetes.
• Nutropin is not for patients who have active cancer or any brain tumors.
• Nutropin is not for patients who are critically ill after open heart surgery or abdominal (stomach) surgery, are severely hurt, or have severe breathing problems.
• Nutropin is not for children and teenagers who have Prader-Willi syndrome and are very overweight or have trouble breathing.
• Patients who are about to start taking Nutropin, or are already taking it, must tell their doctor about all of the medications they are taking, including supplements; if they have or develop a brain tumor; if they are given any new medication — especially cortisone, hydrocortisone, prednisone, prednisolone, dexamethasone, triamcinolone, or betamethasone; if they are pregnant or if they become pregnant; about any other condition or illness they have or develop.
• As with any injection, patients may experience discomfort, soreness, or redness where Nutropin is injected.
• Patients should contact their doctor immediately if they experience ongoing injection site discomfort; curvature of the spine (scoliosis); joint pain; puffy hands and/or feet (caused by fluid retention); changes in vision, a bad headache, or nausea with or without vomiting; hip or knee pain; a need to limp when they walk; pain in wrist (carpel tunnel); allergic reactions.
• Patients must inject Nutropin at a different recommended place on their body each time. The doctor or nurse should supervise the first injection and provide training and instruction.