Milosh

Interview Transcript

Milosh:
"I've sung barbershop now for 31 years. It was one of those wonderful opportunities to provide entertainment to a lot of people.

I had made an appointment for an annual physical, and prior to the annual physical, I had some strange physical manifestations in my stomach. They suggested that I have a CAT scan. The CAT scan that resulted showed that there were these large lymphomas in my abdomen."

Quimby (Milosh's Wife):
"In July of 2006 my husband was diagnosed with large B-cell lymphoma.

Our oncologist introduced us to the idea of Rituxan. He believed in it very strongly and that this was the right treatment. Because of his assurance, we felt confident receiving that particular drug for use."

Milosh:
"They say that I'm in remission since I'm now about two years out from my chemotherapy; everything seems to be going very well."

Quimby (Milosh's Wife):
"There doesn't seem to be anything that he's not able to do. It took a while, of course, after treatment, to build up his strength again, but he's now back to finishing work on his garage that he was building, and he's cutting wood for the fire, and he's going right to life. So it's been a wonderful comeback for him."

Product Indication Rituxan® (Rituximab) is indicated for the treatment of patients with relapsed or refractory, low-grade or follicular, CD20-positive, B-cell non-Hodgkin's lymphoma (NHL) as a single agent; for previously untreated diffuse large B-cell, CD20-positive, NHL in combination with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) or other anthracycline-based chemotherapy regimens; for previously untreated follicular, CD20-positive, B-cell NHL in combination with CVP (cyclophosphamide, vincristine and prednisolone) chemotherapy; and for the treatment of non-progressing (including stable disease), low-grade, CD20-positive, B-cell NHL as a single agent, after first-line CVP chemotherapy.

Important Safety Information, including Boxed WARNINGS Rituxan can cause serious side effects, some of which could be life-threatening:

• Progressive Multifocal Leukoencephalopathy (PML)
  PML is a rare brain infection that usually causes death or severe disability. Patients should call their doctor right away if they notice any new or worsening medical problems, such as a new or sudden change in thinking, walking, strength, vision, or other problems that have lasted over several days. PML can occur during treatment with Rituxan or after treatment has finished. There is no known treatment, prevention, or cure for PML.
• Infusion reactions. Patients should tell their doctor or get medical treatment right away if they get hives, swelling, dizziness, blurred vision, drowsiness, headache, cough, wheezing, or have trouble breathing while receiving or after receiving Rituxan.
• Tumor Lysis Syndrome (TLS). TLS is caused by the fast breakdown of certain types of cancer cells. Patients receiving Rituxan for non-Hodgkin's lymphoma (NHL) may get TLS.
• Severe skin reactions. Patients should tell their doctor or get medical treatment right away if they get any of these symptoms: painful sores on the skin or in the mouth, ulcers, blisters, or peeling skin while receiving or after receiving Rituxan.

Rituxan can cause other serious and life-threatening side effects, including:

• Hepatitis B virus reactivation. Patients should tell their doctor if they had hepatitis B virus or are a carrier of hepatitis B virus. Receiving Rituxan could cause the hepatitis B virus to become an active infection again. This may cause serious liver problems and death. People with active liver disease due to hepatitis B should stop receiving Rituxan.
• Heart problems. Patients should tell their doctor about any heart problems they have including chest pain (angina) and irregular heart beats. Rituxan can cause chest pain and irregular heart beats which may require treatment.
• Infections. Rituxan can increase the chances for getting infections. Patients should call their doctor right away if they have a cough that will not go away, fever, chills, congestion, or any flu-like symptoms while receiving Rituxan. These symptoms may be signs of a serious infection.
• Stomach and bowel problems. Serious stomach and bowel problems have been seen when Rituxan has been used with anti-cancer medicines in some patients with non-Hodgkin's lymphoma. Patients should call their doctor right away if they have any stomach area pain during treatment with Rituxan.

Common side effects during Rituxan infusions include fever, chills and shakes, itching, cough, throat irritation or tightness, headache, nausea, hives, and sneezing. Other side effects with Rituxan include aching joints, upper respiratory tract infection, decreased blood cell counts, and lung problems.

Please see the full Product Information, including Boxed WARNINGS and Medication Guide, for additional safety information.

Individual results may vary.