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Wei-Qiang Gao

Wei-Qiang Gao
Wei-Qiang Gao Senior Scientist: Molecular Biology

Mentor Profile | Top Scientific Papers

Top Scientific Papers

  • Wei D, Levic S, Nie L, Gao WQ, Petit C, Jones EG, Yamoah EN. Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage. Proc Natl Acad Sci U S A 2008 Dec 30; 105(52): 21000-21005. Epub 2008 Dec 8. View Abstract on PubMed

  • Leong KG, Wang BE, Johnson L, Gao WQ. Generation of a prostate from a single adult stem cell. Nature 2008 Dec 11; 456(7223): 804-808. Epub 2008 Oct 22. View Abstract on PubMed

  • Leong KG, Gao WQ. The Notch pathway in prostate development and cancer. Differentiation 2008 Jul; 76(6): 699-716. View Abstract on PubMed

  • Wang BE, Wang XD, Ernst JA, Polakis P, Gao WQ. Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling. PLoS ONE 2008 May 14; 3(5): e2186. View Abstract on PubMed

  • Wang XD, Wang BE, Soriano R, Zha J, Zhang Z, Modrusan Z, Cunha GR, Gao WQ. Expression profiling of the mouse prostate after castration and hormone replacement: implication of H-cadherin in prostate tumorigenesis. Differentiation 2007 Mar; 75(3): 219-34. View Abstract on PubMed

  • Wang XD, Leow CC, Zha J, Tang Z, Modrusan Z, Radtke F, Aguet M, de Sauvage FJ, Gao WQ. Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation. Dev Biol 2006 Feb 1; 290(1): 66-80. View Abstract on PubMed

  • Leow CC, Polakis P, Gao WQ. Role of Hath1, a bHLH transcription factor in colon adenocarcinoma. Ann N Y Acad Sci 2005 1059: 74-183.

  • Leow CC, Wang XD, Gao WQ. Novel method of generating prostate-specific Cre-LoxP gene switching via intraductal delivery of adenovirus. Prostate 2005 Sep 15; 65(1): 1-9. View Abstract on PubMed

  • Zhang Y, Zhai SQ, Shou J, Song W, Sun JH, Guo W, Zheng GL, Hu YY, Gao WQ. Isolation, growth and differentiation of hair cell progenitors from the newborn rat cochlear greater epithelial ridge. J Neurosci Methods 2007 Aug 30; 164(2): 271-9. Epub 2007 May 18. View Abstract on PubMed

  • Leow CC, Romero MS, Ross S, Polakis P, Gao WQ. Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells. Cancer Res 2004 Sep 1; 64(17): 6050-7. View Abstract on PubMed

  • Wang XD, Shou J, Wong P, French DM, Gao WQ. Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement. J Biol Chem 2004 Jun 4; 279(23): 24733-44. View Abstract on PubMed

  • Gao WQ. Hair cell development in higher vertebrates. Curr Top Dev Biol 2003; 57: 293-319. View Abstract on PubMed

  • Wang BE, Shou J, Ross S, Koeppen H, De Sauvage FJ, Gao WQ. Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells. J Biol Chem 2003 May 16; 278(20):1 8506-13. View Abstract on PubMed

  • Shou J, Zheng JL, Gao WQ. Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1. Mol Cell Neurosci 2003 Jun; 23(2): 169-79. View Abstract on PubMed

  • Shou J, Soriano R, Hayward SW, Cunha GR, Williams PM, Gao WQ. Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression. Proc Natl Acad Sci U S A 2002 Mar 5; 99(5): 2830-5. View Abstract on PubMed

  • Shou J, Ross S, Koeppen H, de Sauvage FJ, Gao WQ. Dynamics of notch expression during murine prostate development and tumorigenesis. Cancer Res 2001 Oct 1; 61(19): 7291-7. View Abstract on PubMed

  • Yan M, Wang LC, Hymowitz SG, Schilbach S, Lee J, Goddard A, de Vos AM, Gao WQ, Dixit VM. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science 2000 Oct 20; 290(5491): 523-7. View Abstract on PubMed

  • Zheng JL, Shou J, Guillemot F, Kageyama R, Gao WQ. Hes1 is a negative regulator of inner ear hair cell differentiation. Development 2000 Nov; 127(21): 4551-60. View Abstract on PubMed

  • Zheng JL, Gao WQ. Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 2000 Jun; 3(6): 580-6. View Abstract on PubMed

  • Gao WQ, Shinsky N, Ingle G, Beck K, Elias KA, Powell-Braxton L. IGF-I deficient mice show reduced peripheral nerve conduction velocities, decreased axonal diameters and respond to exogenous IGF-I treatment. J Neurobiol 1999 Apr; 39(1): 142-52. View Abstract on PubMed

  • Zheng JL, Keller G, Gao WQ. Immunocytochemical and morphological evidence for self-repair as an important contributor to mammalian inner ear hair cell recovery. J Neurosci 1999 Mar 15; 19(6): 2161-70. View Abstract on PubMed

  • Gao WQ. Therapeutic potential of neurotrophins for treatment of hearing loss. Mol Neurobiol 1998 Winter; 17(1-3): 17-31. View Abstract on PubMed

  • Xiang M, Gao WQ, Hasson T, Shin JJ. Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development 1998 Oct; 125(20): 3935-46. View Abstract on PubMed

  • Gao WQ, Shinsky N, Armanini MP, Moran P, Zheng JL, Mendoza-Ramirez JL, Phillips HS, Winslow JW, Caras IW. Regulation of hippocampal synaptic plasticity by the tyrosine kinase receptor, REK7/EphA5 and its ligand, AL-1/Ephrin-A5. Mol Cell Neurosci 1998 Aug; 11(5-6): 247-59. View Abstract on PubMed

  • Zheng JL, Helbig C, Gao WQ. Induction of cell proliferation by fibroblast and insulin-like growth factors in pure rat inner ear epithelial cell cultures. J Neurosci 1997 Jan 1; 17(1): 216-26. View Abstract on PubMed

  • Zheng JL, Stewart RR, Gao WQ. Neurotrophin-4/5 enhances survival of cultured spiral ganglion neurons and protects them from cisplatin neurotoxicity. J Neurosci 1995 Jul; 15(7 Pt 2): 5079-87. View Abstract on PubMed

  • Gao WQ, Dybdal N, Shinsky N, Murnane A, Schmelzer C, Siegel M, Keller G, Hefti F, Phillips HS, Winslow JW. Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy. Ann Neurol 1995 Jul; 38(1): 30-7. View Abstract on PubMed

  • Gao WQ, Zheng JL, Karihaloo M. Neurotrophin-4/5 (NT-4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation. J Neurosci 1995 Apr; 15(4): 2656-67. View Abstract on PubMed

  • Gao WQ, Hatten ME. Immortalizing oncogene subverts the control of granule cell lineage in developing cerebellum. Development 1994 May; 120(5): 1059-70. View Abstract on PubMed

  • Gao WQ, Hatten ME. Neuronal differentiation rescued by implantation of weaver granule cell precursors into wild-type cerebellar cortex. Science 1993 Apr 16; 260(5106): 367-9. View Abstract on PubMed

  • Gao WQ, Liu XL, Hatten ME. The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation. Cell 1992 Mar 6; 68(5): 841-54. View Abstract on PubMed

  • Gao WO, Heintz N, Hatten ME. Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron 1991 May; 6(5): 705-15. View Abstract on PubMed

  • Gao WQ, Macagno ER. Axon extension and retraction by leech neurons: Severing early projections to the peripheral targets prevents the normal retraction of other projections. Neuron 1988 Jun; 1(4): 269-77. View Abstract on PubMed