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Lauri Diehl

Lauri Diehl
Lauri Diehl Scientist/Pathologist: Pathology

Mentor Profile | Top Scientific Papers

Top Scientific Papers

  • Noble CL, Abbas AR, Lees CW, Cornelius J, Toy K, Modrusan Z, Clark H, Arnott ID, Penman ID, Satsangi J, Diehl L. The characterization of intestinal gene expression profiles in Crohn's Disease by genome-wide microarray analysis. Inflammatory Bowel Diseases 2010 - in press.

  • Carlsson F, Kim J, Dimitru C, Barack K, Carano R, Sun M, Diehl L, Brown E. Host-detrimental role of Esx-1-mediated inflammasome activation in Mycobacterial infection. PLoS Pathogens 2010 - in press.

  • Li B, Xi H, Diehl L, Lee WP, Sturgeon L, Chinn J, Deforge L, Kelley RF, Wiesmann C, van Lookeren Campagne M, Sidhu SS. Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation. J Biol Chem 2009 Dec 18; 284(51): 35605-11. View Abstract on PubMed

  • Chiang EY, Kolumam GA, Yu X, Francesco M, Ivelja S, Peng I, Gribling P, Shu J, Lee WP, Refino CJ, Balazs M, Paler-Martinez A, Nguyen A, Young J, Barck KH, Carano RA, Ferrando R, Diehl L, Chatterjea D, Grogan JL. Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease. Nat Med 2009 Jul; 15(7): 766-73. View Abstract on PubMed

  • Lees CW, Zacharias WJ, Tremelling M, Noble CL, Nimmo ER, Tenesa A, Cornelius J, Torkvist L, Kao J, Farrington S, Drummond HE, Ho GT, Arnott ID, Appelman HD, Diehl L, Campbell H, Dunlop MG, Parkes M, Howie SE, Gumucio DL, Satsangi J. Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. PLoS Med 2008 Dec 9; 5(12): e239. View Abstract on PubMed

  • Flanagan K, Modrusan Z, Cornelius J, Chavali A, Kasman I, Komuves L, Mo L, Diehl L. Intestinal epithelial cell up-regulation of LY6 molecules during colitis results in enhanced chemokine secretion. J Immunol 2008 Mar 15; 180(6): 3874 -81. View Abstract on PubMed

  • Noble CL, Abbas A, Cornelius J, Lees CW, Toy K, Arnott ID, Modrusan Z, Clark H, Penman I, Satsangi J, Diehl L. Regional Variation in Gene Expression in the Healthy Colon is Dysregulated in Ulcerative Colitis. Gut 2008 Oct; 57(10): 1398-405. Epub 2008 Jun 3. View Abstract on PubMed

  • Seshasayee D, Lee WP, Zhou M, Shu J, Suto E, Zhang J, Diehl L, Austin CD, Meng YG, Tan M, Bullens SL, Seeber S, Fuentes ME, Labrijn AF, Graus YM, Miller LA, Schelegle ES, Hyde DM, Wu LC. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J Clin Invest 2007 Dec; 117(12): 3868-78. View Abstract on PubMed

  • Katschke KJ, Helmy KY, Steffek M, Xi H, Yin J, Lee WP, Gribling P, Barck KH, Carano RA, Taylor RE, Rangell L, Diehl L, Hass PE, Wiesmann C, van Lookerenb Campagne M. A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis. J Exp Med 2007 Jun 11; 204(6): 1319-25. View Abstract on PubMed

  • Helmy KY, Katschke KJ, Gorgani NN, Kljavin NM, Elliott JM, Diehl L, Scales SJ, Ghilardi N, van Lookeren Campagne M. CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell 2006 Mar 10; 124(5): 915-27. View Abstract on PubMed

  • Pisabarro MT, Leung B, Kwong M, Corpuz R, Frantz GD, Chiang N, Vandlen R, Diehl LJ, Skelton N, Kim HS, Eaton D, Schmidt KN. Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods. J Immunol 2006 Feb 15; 176(4): 2069-73. View Abstract on PubMed

  • Gong Q, Ou Q, Ye S, Lee WP, Cornelius J, Diehl L, Lin WY, Hu Z, Lu Y, Chen Y, Wu Y, Meng YG, Gribling P, Lin Z, Nguyen K, Tran T, Zhang Y, Rosen H, Martin F, Chan AC. Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy. J Immunol 2005 Jan 15; 174(2): 817-26.

  • Barck KH, Lee WP, Diehl LJ, Ross J, Gribling P, Zhang Y, Nguyen K, van Bruggen N, Hurst S, Carano RA. Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro-computed tomography and automated image analysis. Arthritis Rheum 2004 Oct; 50(10): 3377-86. View Abstract on PubMed

  • Hasegawa K, Martin F, Huang G, Tumas D, Diehl L, Chan AC. PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science 2004 Jan 30; 303(5658): 685-9. View Abstract on PubMed