Nico Ghilardi Scientist: Molecular Biology Mentor Profile | Top Scientific Papers

Top Scientific Papers

• Batten M, Kljavin NM, Li J, Walter MJ, de Sauvage FJ, Ghilardi N. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells. J Immunol 2008 Mar 1; 180(5): 2752-6. View Abstract on PubMed
  
  
• Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Z, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, Ouyang W. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 2008 Mar; 14(3): 282-9. Epub 2008 Feb 10. View Abstract on PubMed
  
  
• Ghilardi N, Ouyang W. Targeting the development and effector functions of TH17 cells. Semin Immunol 2007 Dec; 19(6): 383-93. Epub 2008 Jan 14. View Abstract on PubMed
  
  
• Broxmeyer HE, Li J, Hangoc G, Cooper S, Tao W, Mantel C, Graham-Evans B, Ghilardi N, de Sauvage FJ. Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31. Exp Hematol 2007 Apr; 35(4 Suppl 1): 78-86. View Abstract on PubMed
  
  
• Perrigouge JG, Li J, Zaph C, Goldschmidt M, Scott P, de Sauvage FJ, Pearch EJ, Ghilardi N, Artis D. IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung. J Exp Med 2007 Mar 19; 204(3): 481-7. Epub 2007 Mar 12. View Abstract on PubMed
  
  
• Batten M, Ghilardi N. The biology and therapeutic potential of interleukin 27. J Mol Med 2007 Jul; 85(7): 661-72. Epub 2007 Feb 10. View Abstract on PubMed
  
  
• Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, Lucas S, Lee J, de Sauvage FJ, Ghilardi N. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 2006 Sep; 7(9): 929-36. Epub 2006 Aug 13. View Abstract on PubMed
  
  
• Ghilardi N, Kljavin N, Chen Q, Lucas S, Gurney AL, de Sauvage FJ. Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice. J Immunol 2004 Mar 1; 172(5): 2827-33. View Abstract on PubMed
  
  
• Lucas S, Ghilardi N, Li J, de Sauvage FJ. IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc Natl Acad Sci U S A 2003 Dec 9; 100(25): 15047-52. Epub 2003 Dec 1. View Abstract on PubMed
  
  
• Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003 Jan 17; 278(3): 1910-4. Epub 2002 Nov 3. View Abstract on PubMed
  
  
• Ghilardi N, Li J, Hongo JA, Yi S, Gurney A, de Sauvage FJ. A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5. J Biol Chem 2002 May 10; 277(19): 16831-6. Epub 2002 Mar 4. View Abstract on PubMed
  
  
• Chen Q, Ghilardi N, Wang H, Baker T, Xie MH, Gurney A, Grewal IS, de Sauvage FJ. Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 2000 Oct 19; 407(6806): 916-20. View Abstract on PubMed