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Wai Lee Wong Director: Assay & Automation Technology |
"I was attracted to Genentech because of its reputation as a great place to do cutting-edge science leading to the development of new therapeutics. Since joining Genentech in December 1987, I have found that not only do I get to develop new assay techniques, but I also get to use them for various challenging and exciting scientific investigations with a group of extremely motivated and highly collaborative people."
Current Projects "Members of the department are involved in a number of early- to late-stage research projects in the areas of oncology, immunology, and vascular biology. The majority of our efforts are focused on developing critical and innovative biochemical and cell-based assay technologies needed to advance projects. We also develop automated systems to perform high throughput assays and manage assay results."
Collaborations "One of the most rewarding projects I have had the opportunity to participate in, from early research to final product, is Herceptin® (Trastuzumab). I worked with scientists like Paul Carter and Len Presta on the humanization of the Herceptin antibody by developing different assays. I particularly enjoyed collaborating with very committed scientists from Research, Regulatory and Clinical on obtaining FDA approval of a diagnostic test for enrolling patients for Herceptin therapy. Currently, I am involved in enhancing the efficacy of anti-tumor antibodies and establishing high throughput assays in support of pharmacokinetic studies and cell line development."
Inspiration/Vision "I am inspired by the knowledge that I am developing novel assays necessary for the advancement of projects. I am further energized by the fact that I am collaborating with highly intelligent individuals who are committed to furthering our knowledge of the molecules under investigation. Over the next five years, I hope the assay techniques established by our department will result in the development of novel and important drugs that can benefit individuals and society in a significant way."