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Nicholas van Bruggen

Nicholas van Bruggen
Nicholas van Bruggen Associate Director: Biomedical Imaging

Profile | Education/Background | Top Scientific Papers | Awards & Honors

Top Scientific Papers

  • Greve JM, Chico TJ, Goldman H, Bunting S, Peale FV Jr, Daugherty A, van Bruggen N, Williams SP. Magnetic resonance angiography reveals therapeutic enlargement of collateral vessels induced by VEGF in a murine model of peripheral arterial disease. J Magn Reson Imaging 2006 Nov; 24(5): 1124-32. View Abstract on PubMed

  • Carano RA, Ross AL, Ross J, Williams SP, Koeppen H, Schwall RH, van Bruggen N. Quantification of tumor tissue populations by multispectral analysis. Magn Reson Med 2004 Mar; 51(3): 542-51. View Abstract on PubMed

  • Street J, Bao M, deGuzman L, Bunting S, Peale FV Jr, Ferrara N, Steinmetz H, Hoeffel J, Cleland JL, Daugherty A, van Bruggen N, Redmond HP, Carano RA, Filvaroff EH. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A 2002 Jul 23; 99(15): 9656-61. View Abstract on PubMed

  • Williams SP, Gerber HP, Giordano FJ, Peale FV Jr, Bernstein LJ, Bunting S, Chien KR, Ferrara N, van Bruggen N. Dobutamine stress cine-MRI of cardiac function in the hearts of adult cardiomyocyte-specific VEGF knockout mice. J Magn Reson Imaging 2001 Oct; 14(4): 374-82. View Abstract on PubMed

  • van Lookeren Campagne M, Thomas GR, Thibodeaux H, Palmer JT, Williams SP, Lowe DG, van Bruggen N. Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat. J Cereb Blood Flow Metab 1999 Dec; 19(12): 1354-64. View Abstract on PubMed

  • van Bruggen N, Thibodeaux H, Palmer JT, Lee WP, Fu L, Cairns B, Tumas D, Gerlai R, Williams SP, van Lookeren Campagne M, Ferrara N. VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. J Clin Invest 1999 Dec; 104(11): 1613-20. View Abstract on PubMed

  • Palmer JT, de Crespigny AJ, Williams S, Busch E, van Bruggen N. High-resolution mapping of discrete representational areas in rat somatosensory cortex using blood volume-dependent functional MRI. Neuroimage 1999 Apr; 9(4): 383-92. View Abstract on PubMed

  • van Bruggen N, Busch E, Palmer JT, Williams SP, de Crespigny AJ. High-resolution functional magnetic resonance imaging of the rat brain: mapping changes in cerebral blood volume using iron oxide contrast media. J Cereb Blood Flow Metab 1998 Nov; 18(11): 1178-83. View Abstract on PubMed

  • Pham CD, Roberts TP, van Bruggen N, Melnyk O, Mann J, Ferrara N, Cohen RL, Brasch RC. Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor. Cancer Invest 1998; 16(4): 225-30. View Abstract on PubMed

  • Brasch R, Pham C, Shames D, Roberts T, van Dijke K, van Bruggen N, Mann J, Ostrowitzki S, Melnyk O. Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J Magn Reson Imaging 1997 Jan-Feb; 7(1): 68-74. View Abstract on PubMed

  • King MD, Houseman J, Roussel SA, van Bruggen N, Williams SR, Gadian DG. q-Space imaging of the brain. Magn Reson Med 1994 Dec; 32(6): 707-13. View Abstract on PubMed

  • van Bruggen N, Roberts TP, Cremer JE. The application of magnetic resonance imaging to the study of experimental cerebral ischaemia. Cerebrovasc Brain Metab Rev 1994 Summer; 6(2): 180-210. View Abstract on PubMed

  • Gardner-Medwin AR, van Bruggen N, Williams SR, Ahier RG. Magnetic resonance imaging of propagating waves of spreading depression in the anaesthetised rat. J Cereb Blood Flow Metab 1994 Jan; 14(1): 7-11. View Abstract on PubMed

  • Kauppinen RA, Williams SR, Busza AL, van Bruggen N. Applications of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology. Trends Neurosci 1993 Mar; 16(3): 88-95. View Abstract on PubMed

  • King MD, van Bruggen N, Busza AL, Houseman J, Williams SR, Gadian DG. Perfusion and diffusion MR imaging. Magn Reson Med 1992 Apr; 24(2): 288-301. View Abstract on PubMed

  • van Bruggen N, Cullen BM, King MD, Doran M, Williams SR, Gadian DG, Cremer JE. T2- and diffusion-weighted magnetic resonance imaging of a focal ischemic lesion in rat brain. Stroke 1992 Apr; 23(4): 576-82. View Abstract on PubMed

  • van Bruggen N, Chan WS, Syha J, Marshall JF, Proctor E, Williams SR, Gadian DG, Hart IR. Cell and tissue responses of a murine tumour to phthalocyanine-mediated photodynamic therapy. Eur J Cancer 1992; 28(1): 42-6. View Abstract on PubMed

  • Doran M, Hajnal JV, Van Bruggen N, King MD, Young IR, Bydder GM. Normal and abnormal white matter tracts shown by MR imaging using directional diffusion weighted sequences. J Comput Assist Tomogr 1990 Nov-Dec; 14(6): 865-73. View Abstract on PubMed

Book

  • van Bruggen N and Roberts TPL, editors. Biomedical Imaging in Experimental Neuroscience. CRC Press 2002 Dec. (Frontiers in Neuroscience Volume: 18)