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Menno van Lookeren Campagne Senior Scientist: Immunology |
Top Scientific Papers
- Xi H, Katschke KJ Jr, Helmy KY, Wark PA, Kljavin N, Clark H, Eastham-Anderson J, Shek T, Roose-Girma M, Ghilardi N, van Lookeren Campagne M. Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1. J Exp Med 2010 Jan 18; 207(1): 7-16, S1-5. View Abstract on PubMed
- Li B, Xi H, Diehl L, Lee WP, Sturgeon L, Chinn J, Deforge L, Kelley RF, Wiesmann C, van Lookeren Campagne M, Sidhu SS. Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation. J Biol Chem 2009 Dec 18; 284(51): 35605-11. View Abstract on PubMed
- Katschke KJ Jr, Stawicki S, Yin J, Steffek M, Xi H, Sturgeon L, Hass PE, Loyet KM, Deforge L, Wu Y, van Lookeren Campagne M, Wiesmann C. Structural and functional analysis of a C3b-specific antibody that selectively inhibits the alternative pathway of complement. J Biol Chem 2009 Apr 17; 284(16): 10473-9. View Abstract on PubMed
- Gorgani NN, He JQ, Katschke KJ Jr, Helmy KY, Xi H, Steffek M, Hass PE, van Lookeren Campagne M. Complement receptor of the Ig superfamily enhances complement-mediated phagocytosis in a subpopulation of tissue resident macrophages. J Immunol 2008 Dec 1; 181(11): 7902-8. View Abstract on PubMed
- Kim DD, Miwa T, Kimura Y, Schwendener RA, van Lookeren Campagne M, Song WC. Deficiency of DAF and Crry on murine platelets leads to complement-dependent clearance via the macrophage phagocytic receptor CRIg. Blood 2008 Aug 15; 112(4): 1109-19. View Abstract on PubMed
- van Lookeren Campagne M, Wiesmann C, Brown EJ. Macrophage complement receptors and pathogen clearance. Cell Microbiol 2007 Sep; 9(9): 2095-102. View Abstract on PubMed
- Katschke KJ, Helmy KY, Steffek M, Xi H, Yin J, Lee WP, Gribling P, Barck KH, Carano RA, Taylor RE, Rangell L, Diehl L, Hass PE, Wiesmann C, van Lookeren Campagne M. A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis. J Exp Med 2007 Jun 11; 204(6): 1319-25. View Abstract on PubMed
- Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M. Structure of C3b in complex with CRIg gives insights into regulation of complement activation. Nature 2006 Nov 9; 444(7116): 217-20. View Abstract on PubMed
- Helmy KY, Katschke KJ, Gorgani NN, Kljavin NM, Elliott JM, Diehl L, Scales SJ, Ghilardi N, van Lookeren Campagne M. CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell 2006 Mar 10; 124(5): 915-27. View Abstract on PubMed
- Campagne MV, Thibodeaux H, van Bruggen N, Cairns B, Lowe DG. Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion. J Neurosci 2000 Jul 15; 20(14): 5200-7. View Abstract on PubMed
- van Lookeren Campagne M, Thibodeaux H, van Bruggen N, Cairns B, Gerlai R, Palmer JT, Williams SP, Lowe DG. Evidence for a protective role of metallothionein-1 in focal cerebral ischemia. Proc Natl Acad Sci U S A 1999 Oct 26; 96(22): 12870-5. View Abstract on PubMed