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Melissa Starovasnik

Melissa Starovasnik
Melissa Starovasnik Director: Protein Engineering

Profile | Education/Background | Top Scientific Papers | Awards & Honors

Top Scientific Papers

  • Lin WY, Gong Q, Seshasayee D, Lin Z, Ou Q, Ye S, Suto E, Shu J, Lee WP, Lee CW, Fuh G, Leabman M, Iyer S, Howell K, Gelzleichter T, Beyer J, Danilenko D, Yeh S, DeForge LE, Ebens A, Thompson JS, Ambrose C, Balazs M, Starovasnik MA, Martin F. Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade. Blood 2007 Dec 1; 110(12): 3959-67. View Abstract on PubMed

  • Lee CV, Hymowitz SG, Wallweber HJ, Gordon NC, Billeci KL, Tsai SP, Compaan DM, Yin J, Gong Q, Kelley RF, DeForge LE, Martin F, Starovasnik MA, Fuh G. Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells. Blood 2006 Nov 1; 108(9): 3103-11. View Abstract on PubMed

  • Hymowitz SG, Patel DR, Wallweber HJ, Runyon S, Yan M, Yin J, Shriver SK, Gordon NC, Pan B, Skelton NJ, Kelley RF, Starovasnik MA. Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J Biol Chem 2005 Feb 25; 280(8): 7218-27. View Abstract on PubMed

  • Stamos J, Eigenbrot C, Nakamura GR, Reynolds ME, Yin J, Lowman HB, Fairbrother WJ, Starovasnik MA. Convergent recognition of the IgE binding site on the high-affinity IgE receptor. Structure (Camb) 2004 Jul; 12(7): 1289-301. View Abstract on PubMed

  • Gordon NC, Pan B, Hymowitz SG, Yin J, Kelley RF, Cochran AG, Yan M, Dixit VM, Fairbrother WJ, Starovasnik MA. BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site. Biochemistry 2003 May 27; 42(20): 5977-83. View Abstract on PubMed

  • Kayagaki N, Yan M, Seshasayee D, Wang H, Lee W, French DM, Grewal IS, Cochran AG, Gordon NC, Yin J, Starovasnik MA, Dixit VM. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 2002 Oct; 17(4): 515-24. View Abstract on PubMed

  • Nakamura GR, Reynolds ME, Chen YM, Starovasnik MA, Lowman HB. Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor. Proc Natl Acad Sci U S A 2002 Feb 5; 99(3): 1303-8.

  • Hymowitz SG, Filvaroff EH, Yin J, Lee J, Cai L, Risser P, Maruoka M, Mao W, Foster J, Kelley RF, Pan G, Gurney AL, de Vos AM, Starovasnik MA. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J 2001 Oct 1; 20(19): 5332-41. View Abstract on PubMed

  • Cochran AG, Skelton NJ, Starovasnik MA. Tryptophan zippers: stable, monomeric beta-hairpins. Proc Natl Acad Sci U S A 2001 May 8; 98(10): 5578-83. View Abstract on PubMed

  • Starovasnik MA, Braisted AC, Wells JA. Structural mimicry of a native protein by a minimized binding domain. Proc Natl Acad Sci U S A 1997 Sep 16; 94(19): 10080-5. View Abstract on PubMed