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Mike Costa

Mike Costa
Mike Costa Senior Sceintist: Cancer Targets

Profile | Education/Background | Top Scientific Papers | Awards & Honors

Top Scientific Papers

  • Lackner MR, Kindt RM, Carroll PM, Brown K, Cancilla MR, Chen C, de Silva H, Franke Y, Guan B, Heuer T, Hung T, Keegan K, Lee JM, Manne V, O'Brien C, Parry D, Perez-Villar JJ, Reddy RK, Xiao H, Zhan H, Cockett M, Plowman G, Fitzgerald K, Costa M, Ross-Macdonald P. Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors. Cancer Cell 2005 Apr ;7(4): 325-36. View Abstract on PubMed

  • Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev 2001 Mar 15; 15(6): 672-86. View Abstract on PubMed

  • Costa M, Raich W, Agbunag C, Leung B, Hardin J, Priess JR. A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J Cell Biol 1998 Apr 6; 141(1): 297-308. View Abstract on PubMed

  • Morize P, Christiansen AE, Costa M, Parks S, Wieschaus E. Hyperactivation of the folded gastrulation pathway induces specific cell shape changes. Development 1998 Feb; 125(4): 589-97. View Abstract on PubMed

  • Kenyon CJ, Austin J, Costa M, Cowing DW, Harris JM, Honigberg L, Hunter CP, Maloof JN, Muller-Immerglück MM, Salser SJ, Waring DA, Wang BB, Wrischnik LA. The dance of the Hox genes: patterning the anteroposterior body axis of Caenorhabditis elegans. Cold Spring Harb Symp Quant Biol 1997; 62: 293-305. View Abstract on PubMed

  • Costa M, Wilson ET, Wieschaus E. A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation. Cell 1994 Mar 25; 76(6): 1075-89. View Abstract on PubMed

  • Costa M, Sweeton D, Wieschaus E. Gastrulation in Drosophila: cellular mechanisms of morphogenetic movements. In: Bate M, Martinez-Arias A, editors. The development of Drosophila melanogaster. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press; 1993. p. 425-66.

  • Wieschaus E, Parks S, Costa M, Sweeton D. (1991). Genes controlling cell shape changes during gastrulation in Drosophila melanogaster. In: Gerhart J, editor. Cell-cell interactions in early development. New York: Wiley-Liss; 1991.

  • Wieschaus E, Sweeton D, Costa M. Convergence and extension during germ band elongation in Drosophila embryos. In: Keller R, Clark W Jr, Griffini F, editors. Gastrulation: movements, patterns, and molecules. New York: Plenum Press; 1991. p. 213-23.

  • Sweeton D, Parks S, Costa M, Wieschaus E. Gastrulation in Drosophila: the formation of the ventral furrow and posterior midgut invaginations. Development 1991 Jul; 112(3): 775-89. View Abstract on PubMed

  • Costa M, Weir M, Coulson A, Sulston J, Kenyon C. Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox. Cell 1988 Dec 2; 55(5): 747-56. View Abstract on PubMed