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Maureen Beresini

Maureen Beresini
Maureen Beresini Senior Scientist: Biochemical Pharmacology

Profile | Education/Background | Top Scientific Papers | Awards & Honors

Top Scientific Papers

  • Keating SM, Clark KR, Stefanich LD, Arellano F, Edwards CP, Bodary SC, Spencer SA, Gadek TR, Marsters JC Jr, Beresini MH. Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the alphal subunit of lymphocyte function-associated antigen-1. Protein Sci 2006 Feb; 15(2): 290-303. View Abstract on PubMed

  • Olivero AG, Eigenbrot C, Goldsmith R, Robarge K, Artis DR, Flygare J, Rawson T, Sutherlin DP, Kadkhodayan S, Beresini M, Elliott LO, DeGuzman GG, Banner DW, Ultsch M, Marzec U, Hanson SR, Refino C, Bunting S, Kirchhofer D. A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo. J Biol Chem 2005 Mar 11; 280(10): 9160-9. View Abstract on PubMed

  • Zobel K, Koehler MF, Beresini MH, Caris LD, Combs D. Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo. Bioorg Med Chem Lett 2003 May 5; 13(9): 1513-5. View Abstract on PubMed

  • Gadek TR, Burdick DJ, McDowell RS, Stanley MS, Marsters JC Jr, Paris KJ, Oare DA, Reynolds ME, Ladner C, Zioncheck KA, Lee WP, Gribling P, Dennis MS, Skelton NJ, Tumas DB, Clark KR, Keating SM, Beresini MH, Tilley JW, Presta LG, Bodary SC. Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule. Science 2002 Feb 8; 295(5557): 1086-9. View Abstract on PubMed

  • Koehler MF, Zobel K, Beresini MH, Caris LD, Combs D, Paasch BD, Lazarus RA. Albumin affinity tags increase peptide half-life in vivo. Bioorg Med Chem Lett 2002 Oct 21; 12(20): 2883-6. View Abstract on PubMed

  • Keating SM, Marsters J, Beresini M, Ladner C, Zioncheck K,Clark K, Arellano F, Bodary S. Putting the pieces together: contribution of fluorescence polarization assays to small-molecule lead optimization Proc. SPIE-Int. Soc. Opt. Eng 2000; 3913: 128-137.

  • Quan C, Skelton NJ, Clark K, Jackson DY, Renz ME, Chiu HH, Keating SM, Beresini MH, Fong S, Artis DR. Transfer of a protein binding epitope to a minimal designed peptide. Biopolymers 1998; 47(4): 265-75. View Abstract on PubMed

  • Cho CY, Youngquist RS, Paikoff SJ, Beresini MH, Hebert AR, Berleau LT, Liu CW, Wemmer DE, Keough T, Schultz PG. Synthesis and screening of linear and cyclic oligocarbamate libraries. Discovery of high affinity ligands for GPIIb/IIIa. J Am Chem Soc 1998; 120(31): 7706-7718.

  • Beresini M H, Sadick MD, Galloway AL, Yen R, Yeh SH, Chang AC, Shelton DL,.Wong, W LT. Assays for small molecule agonists and antagonists of the neurotrophin receptors. High Throughput Screening 1997; 329-343.

  • Kumar A, Beresini MH, Dhawan P, Mehta KD. Alpha-subunit of farnesyltransferase is phosphorylated in vivo: effect of protein phosphatase-1 on enzymatic activity. Biochem Biophys Res Commun 1996 May 15; 222(2): 445-52. View Abstract on PubMed

  • Beresini MH, Davalian D, Alexander S, Toton-Quinn R, Barnett B, Cerelli MJ, Hu MW, Berger DE, Blohm WP, Jaklitsch A. Evaluation of EMIT Cyclosporine Assay for use with whole blood. Clin Chem 1993 Nov; 39(11 Pt 1): 2235-41. View Abstract on PubMed

  • Beresini MH, Lempert MJ, Epstein LB. Overlapping polypeptide induction in human fibroblasts in response to treatment with interferon-alpha, interferon-gamma, interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor. J Immunol 1988 Jan 15; 140(2): 485-93. View Abstract on PubMed

  • Hearne M, Benisek WF. Use of a solid-phase photoaffinity reagent to label a steroid binding site: application to the delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni. Biochemistry 1985 Dec 17; 24(26): 7511-6. View Abstract on PubMed