Cris Lewis Director: Biochemical Pharmacology Profile | Education/Background | Top Scientific Papers | Awards & Honors

Top Scientific Papers

• Kothe M, Kohls D, Low S, Coli R, Cheng AC, Jacques SL, Johnson TL, Lewis C, Loh C, Nonomiya J, Sheils AL, Verdries KA, Wynn TA, Kuhn C, Ding YH. Structure of the catalytic domain of human polo-like kinase 1. Biochemistry 2007 May 22; 46(20): 5960-71. View Abstract on PubMed
  
  
• Li H, Tatlock J, Linton A, Gonzalez J, Borchardt A, Dragovich P, Jewell T, Prins T, Zhou R, Blazel J, Parge H, Love R, Hickey M, Doan C, Shi S, Duggal R, Lewis C, Fuhrman S. Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. Bioorg Med Chem Lett 2006 Sep 15; 16(18): 4834-8. View Abstract on PubMed
  
  
• Babine RE, Bleckman TM, Littlefield ES, Parge, HE, Pelletier LAK, Lewis CT, French JV, Imbacuan M, Katoh S, Tatlock JH, Showalter RE, Villfranca JE. Design, synthesis and X-Ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands. Bioorg Medicinal Chem Lett 1996 6: 385-390.
  
  
• Dragovich PS, Barker JE, French J, Imbacuan M, Kalish VJ, Kissinger CR, Knighton DR, Lewis CT, Moomaw EW, Parge HE, Pelletier LA, Prins TJ, Showalter RE, Tatlock JH, Tucker KD, Villafranca JE. Structure-based design of novel, urea-containing FKBP12 inhibitors. J Med Chem 1996 Apr 26; 39(9): 1872-84. View Abstract on PubMed
  
  
• Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature 1995 Dec 7; 378(6557): 641-4. View Abstract on PubMed
  
  
• Lewis C, Krämer T, Robinson S, Hilvert D. Medium effects in antibody-catalyzed reactions. Science 1991 Aug 30; 253(5023): 1019-22. View Abstract on PubMed