Lesley Murray Principal Project Manager: Drug Metabolism & Pharmacokinetics Profile | Education/Background | Top Scientific Papers

Top Scientific Papers

• Hoeflich KP, Gray DC, Eby MT, Tien JY, Wong L, Bower J, Gogineni A, Zha J, Cole MJ, Stern HM, Murray LJ, Davis DP, Seshagiri S. Oncogenic BRAF is required for tumor growth and maintenance in melanoma models. Cancer Res 2006 Jan 15; 66(2): 999-1006. View Abstract on PubMed
  
  
• Murray LJ, Abrams TJ, Long KR, Ngai TJ, Olson LM, Hong W, Keast PK, Brassard JA, O'Farrell AM, Cherrington JM, Pryer NK. SU11248 inhibits tumor growth and CSF-1R-dependent osteolysis in an experimental breast cancer bone metastasis model. Clin Exp Metastasis 2003; 20(8): 757-66. View Abstract on PubMed
  
  
• Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, Schreck RE, Abrams TJ, Ngai TJ, Lee LB, Murray LJ, Carver J, Chan E, Moss KG, Haznedar JO, Sukbuntherng J, Blake RA, Sun L, Tang C, Miller T, Shirazian S, McMahon G, Cherrington JM. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003 Jan; 9(1): 327-37. View Abstract on PubMed
  
  
• Murray L, Luens K, Tushinski R, Jin L, Burton M, Chen J, Forestell S, Hill B. Optimization of retroviral gene transduction of mobilized primitive hematopoietic progenitors by using thrombopoietin, Flt3, and Kit ligands and RetroNectin culture. Hum Gene Ther 1999 Jul 20; 10(11): 1743-52. View Abstract on PubMed
  
  
• Murray LJ, Young JC, Osborne LJ, Luens KM, Scollay R, Hill BL. Thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized CD34+ cells and recruit primitive CD34+ Thy-1+ cells into rapid division. Exp Hematol 1999 Jun; 27(6): 1019-28. View Abstract on PubMed
  
  
• Vadhan-Raj S, Murray LJ, Bueso-Ramos C, Patel S, Reddy SP, Hoots WK, Johnston T, Papadopolous NE, Hittelman WN, Johnston DA, Yang TA, Paton VE, Cohen RL, Hellmann SD, Benjamin RS, Broxmeyer HE. Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer. Ann Intern Med 1997 May 1; 126(9): 673-81. View Abstract on PubMed
  
  
• Young JC, Bruno E, Luens KM, Wu S, Backer M, Murray LJ. Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+Thy-1+Lin- primitive progenitor cells. Blood 1996 Sep 1;88(5): 1619-31. View Abstract on PubMed
  
  
• Murray L, Chen B, Galy A, Chen S, Tushinski R, Uchida N, Negrin R, Tricot G, Jagannath S, Vesole D, Barlogie B, Hoffman R, Tsukamoto A. Enrichment of human hematopoietic stem cell activity in the CD34+Thy-1+Lin- subpopulation from mobilized peripheral blood. Blood 1995 Jan 15; 85(2): 368-78. View Abstract on PubMed
  
  

Books

• Tsukamoto A S, Van Den Berg D, Reading C, Tong J, Murray L, Carella A, Frassoni F, Snyder D, Herzig G, Gorin C, LaPorte J, Negrin R, Blume K, Cunningham I, Claxton D, Deisseroth A, Hoffman R. Isolation of both normal and leukemic cells within the hematopoietic stem cell compartment of chronic myelogenous leukemia mobilized peripheral blood. In "Autologous Stem Cell Transplantation. Biological and Clinical Results in Malignancies". Ed Angelo M. Carella, Harwood Academic. 1997. p. 27
  
  
• Swerdlow S H and Murray, L J. Low-grade lymphomas. In "Malignant lymphomas" (Current Problems in Tumor Pathology). Eds. J A Habeshaw and I Lauder. Churchill Livingstone, Edinburgh, London, Melbourne and New York. 1988, p. 127-168