/ Medical Professionals


Rigorous and groundbreaking science has always been at the core of what we do at Genentech. Our R&D activities are focused on applying excellent science to discover and develop potential new medicines with the goal of becoming first-in-class or best-in-class therapeutics.

  • Oncology
  • Immunology
  • Neuroscience
  • Metabolism
  • Infectious Disease
  • Ophthalmology
Managed by Roche
Molecule Indication Phase
Alectinib ALK+ metastatic non-small cell lung cancer *
Anti-Ly6E Antibody Drug Conjugate HER2-negative breast cancer and non-small cell lung cancer
Anti-OX40 MAb Solid tumors
Anti-STEAP1 Antibody drug conjugate

Prostate cancer

Antibody drug conjugate Pancreatic and ovarian cancers
Atezolizumab Solid tumors *
Metastatic melanoma *

1st line glioblastoma multiforme


1st line metastatic ovarian cancer


Adjuvant breast cancer, HER2-negative


Adjuvant breast cancer, HER2-positive


Adjuvant non-small cell lung cancer


High-risk carcinoid

ChK1 Inhibitor (GDC-0575)

Solid tumors

Cobimetinib Solid tumors *
Metastatic melanoma *
Duligotuzmab (Anti-HER3/EGFR DAF MAb) Solid tumors with mutant KRAS
ERK Inhibitor (GDC-0994) Solid tumors

1st line metastatic non-small cell lung cancer, EGFR mutation positive

IDO Inhibitor (GDC-0919) Solid tumors
Ipatasertib Solid tumors
Gastric cancer
Triple negative breast cancer
Prostate cancer
Lifastuzumab vedotin Platinum-resistant ovarian cancer
Non-small cell lung cancer and ovarian cancer

Diffuse large B-cell lymphoma


Front-line indolent non-Hodgkin's lymphoma


Refractory indolent Non Hodgkin's lymphoma


Front-line chronic lymphocytic leukemia


Early HER2-positive breast cancer


HER2-positive gastric cancer


2nd line HER2-positive metastatic breast cancer

Polatuzumab vedotin Non-Hodgkin's lymphoma and diffuse large B-cell lymphoma *
SERD (GDC-0810) ER+ HER2-negative breast cancer
SERD (GDC-0927) ER+ HER2-negative breast cancer
Taselisib HER2-negative metastatic breast cancer *
Solid tumors and HR+ breast cancer *
Trastuzumab emtansine

1st line HER2-positive metastatic breast cancer


3rd line HER2-positive metastatic breast cancer


Adjuvant metastatic melanoma, BRAF mutation positive


Papillary thyroid cancer, BRAF mutation positive


Metastatic melanoma, BRAF mutation positive


Chronic lymphocytic leukemia and non-Hodgkin's lymphoma


Operable basal cell carcinoma

Etrolizumab Ulcerative colitis *
GDC-3280 Fibrosis

Severe asthma

New Molecular Entity Inflammatory Diseases
Obinutuzumab Lupus Nephritis
Omalizumab Chronic idiopathic urticaria *
Rituximab Pemphigus Vulgaris
Sodium Hyaluronate


Tocilizumab Early rheumatoid arthritis *
Systemic sclerosis *
Giant Cell Arteritis *
Crenezumab Alzheimer's Disease *
Gantenerumab Alzheimer's Disease *
Nav1.7 Inhibitor (GDC-0276) Pain

Primary progressive multiple sclerosis


Relapsing multiple sclerosis


Type 2 diabetes

Anti-Influenza A Influenza
Lampalizumab Geographic atrophy associated with advanced age-related macular degeneration *

Sustained delivery age-related macular degeneration/retinal vein occlusion/diabetic macular edema

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Partner with Us

Approximately 50% of our pipeline and marketed products involve some kind of collaboration.