/ Scientists

Focus on Immunology

We're constantly growing our expertise in Immunology so that we can continue to discover and develop innovative medicines for patients living with debilitating diseases, such as rheumatoid arthritis or asthma.

Our research and discovery efforts include aspects of both innate and adaptive immunity. The greater our understanding of basic mechanisms of immune cell function the more scientific opportunities arise to affect immune function for the treatment of autoimmune and oncologic indications.

Recent Accomplishments

Molecule: Anti-M1 prime Phase IIb COSTA study initiated for allergic asthma

Anti-M1 prime is a humanized monoclonal antibody, targeting the IgE pathway, that binds to the M1 prime segment of membrane IgE. Anti-M1 prime is designed to eliminate the B cells that would develop into plasma cells and produce IgE, rather than binding to and neutralizing existing IgE.

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Publication: Nature Immunology, October 2011

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

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