I joined Genentech in June of 2006 with the task of building a Small Molecule Analytical Chemistry group, which is an integral part of Small Molecule Pharmaceutical Sciences - along with the Pharmaceutics, Process Chemistry and Scale-Up groups.

I was excited by the opportunity to join a company known for its excellent science and track record in fighting life-threatening diseases - especially cancer. Genentech is respected for its exceptionally strong biology and knowledge of large molecule drugs, but this was a chance to be part of an exciting new direction - utilizing the excellent biological understanding of a target to develop new small molecule therapeutics. I am privileged to be part of an enthusiastic team of great scientists in a collaborative and science-driven culture dedicated to one thing: fighting human diseases.

• My Focus

  My team and I are currently working on a broad range of drug candidates mainly with a focus on oncology. A large part of my current work is recruiting and building a world-class team of analytical chemists. The group is steadily growing and we have recently moved into new, state-of-the-art laboratories.

• Publications

  • Effect of Sulfobutyl Ether Beta-Cyclodextrin Modifier on Selectivity of Reversed Phase HPLC Separations

    Journal of Liquid Chromatography & Related Technologies, 2012, ISSN: 1082-6076

    Ngim, Kenley K.; Zhong, Qiqing; Mistry, Kavita; Chetwyn, Nik

     View on PubMed

  • Strategies for the analysis of highly reactive pinacolboronate esters

    Journal of Chromatography A, 2012, ISSN: 0021-9673

    Zhong, Qiqing; Ngim, Kenley K.; Sun, Megan; Li, Jane; Deese, Alan; Chetwyn, Nik P.

     View on PubMed

  • Simultaneous determination of positive and negative pharmaceutical counterions using mixed-mode chromatography coupled with charged aerosol detector.

    Journal of Chromatography, 2010, ISSN: 1873-3778

    Zhang, K.; Dai, L.; Chetwyn, N.

  • A Generic Headspace GC Method for Residual Solvents in Pharmaceuticals: Benefits, Rationale, and Adaptations for New Chemical Entities.

    LC GC North America, 2010, ISSN: 1527-5949

    Dai, L.; Quiroga, A.C.; Zhang, K.; Runes, H.B.; Yazzie, D.T.; Mistry, K.; Chetwyn, N.P.; Dong, M.W.

• Education
  • The University of Kansas, Lawrence, KS. Pharmaceutical Chemistry, Ph.D. – 1997
  • The University of Kansas, Lawrence, KS. Pharmaceutical Chemistry, M.S. – 1994
  • University of Sunderland, Sunderland, U.K. Chemical and Pharmaceutical Sciences,, B.Sc. – 1992
• Awards & Honors
  • Pfizer Site Recognition Award – 1997
  • A.W. Davidson Outstanding Graduate Student Award – 1994
  • IAPBA Graduate Fellowship – 1994
  • Procter and Gamble Graduate Fellowship – 1994
  • Glaxo Prize and Pfizer Prize: First in Class Graduation and Best Undergraduate Research Thesis – 1992
  • PhRMA Fellowship – 1992