UNDERSTANDING BLADDER CANCER

Bladder cancer is the sixth most common form of cancer in the U.S.1 However, prior to 2016, no new treatments had been approved by the FDA in more than 30 years for people with the most advanced form of the disease. 2,3,4

ABOUT BLADDER CANCER

Bladder cancer typically begins in the bladder's innermost layer, the urothelium.5

Bladder, Urothelium
UROTHELIAL CARCINOMA
IS BY FAR THE

MOST COMMON

TYPE OF BLADDER CANCER.5

More advanced stages of bladder cancer are associated with the cancer spreading to the deeper layers and nearby organs, which can make them more difficult to treat.

BLADDER CANCER AFFECTS MOSTLY MEN AND OLDER PEOPLE

MEN ARE ABOUT

3-4x

more likely to get bladder
cancer than women.6

55+
ABOUT

90%

of people with bladder cancer are older than 55 years old.6

  • ABOUT

    81,190

    new cases of bladder cancer will be diagnosed this year, and 6

    Each person represents 10,000 people

  • ABOUT

    11%

    of new diagnoses are made when bladder cancer is in advanced stages.1

RECOGNIZE THE RISK FACTORS

Smokers are 4-7x

MORE LIKELY TO GET THE DISEASE THAN NONSMOKERS7

Additional risk factors include:7,8

  • MALE
    GENDER

  • ADVANCED
    AGE

  • CAUCASIAN ETHNICITY

  • WORKPLACE EXPOSURE

EARLY DIAGNOSIS IS CRITICAL

There is a dramatic difference in relative 5-year survival rates between early and advanced bladder cancer.

  • Stage I
    APPROXIMATELY

    88%

    of people will live five or more years when diagnosed with the earliest stage of the disease, compared to

  • Stage III-IV
    APPROXIMATELY

    15%

    when diagnosed in advanced stages of the disease.9

MORE TREATMENT OPTIONS

PRIOR TO 2016, THE AVAILABLE TREATMENT OPTIONS FOR ADVANCED BLADDER CANCER WERE:10

  • SURGERY

  • CHEMOTHERAPY

  • RADIATION

After more than three decades since new medicines had been approved for advanced bladder cancer, people with advanced bladder cancer can now talk to their doctor about a type of treatment option called immunotherapy.2,3,4,11

The goal of immunotherapy is to work with the body's own immune system in the fight against cancer.

Cancer cell, immune system cell

References: 1 SEER Stat Fact Sheets: Bladder Cancer. National Cancer Institute website. http://seer.cancer.gov/statfacts/html/urinb.html Accessed May 11, 2018. 2 Guancial EA, et al. Journal of Clinical Interventions in Aging. 2015;10:939-949. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467651/. Accessed December 9, 2015. 3 National Cancer Institute. Drugs Approved for Bladder Cancer. http://www.cancer.gov/about-cancer/treatment/drugs/bladder. Accessed December 9, 2015. 4 CenterWatch. FDA Approved Drugs for Oncology. https://www.centerwatch.com/drug-information/fda-approved-drugs/therapeutic-area/12/oncology. Accessed December 9, 2015. 5 American Cancer Society. What is bladder cancer? https://www.cancer.org/cancer/bladder-cancer/about/what-is-bladder-cancer.html. Accessed January 4, 2018. 6 American Cancer Society. Key statistics for bladder cancer. https://www.cancer.org/cancer/bladder-cancer/about/key-statistics.html. Accessed January 4, 2018. 7 American Society of Clinical Oncology. Bladder Cancer: Risk Factors. http://www.cancer.net/cancer-types/bladder-cancer/risk-factors. Accessed October 1, 2017. 8 American Cancer Society. Bladder Cancer Risk Factors. https://www.cancer.org/cancer/bladder-cancer/causes-risks-prevention/riskfactors.html. Accessed January 4, 2018. 9 American Cancer Society. Survival Rates for Bladder Cancer. https://www.cancer.org/cancer/bladder-cancer/detectiondiagnosis-staging/survival-rates.html. Accessed January 4, 2018. 10 American Society of Clinical Oncology. Bladder Cancer: Treatment Options. http://www.cancer.net/cancer-types/bladder-cancer/treatment-options. Accessed October 1, 2017. 11 American Cancer Society. What’s new in bladder cancer research? http://www.cancer.org/cancer/bladdercancer/detailedguide/bladder-cancer-new-research. Accessed January 4, 2018.

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