/* smaller than iPad (768px) */
@media only screen and (max-device-width : 767px) { 
  .game {  

 	}
 body{
 	font-size: 80%;
 }
}



body {
  font-family: "TradeGothicNextW01-Ligh 693250", sans-serif;
  background-color: #f3ede4;
  color: white;
}

.top {
  position: relative;
  width: 100%;
  top: 0;
  z-index: 3;
  max-width: 1280px;
  margin: 0 auto;
}

.label {
  visibility: hidden;
  opacity: 0;
  float: left;
  width: 50%;
  color: #7dc99e;
  text-align: center;
  padding: 20px 0;
  text-transform: uppercase;
  font-family: "Trade Gothic Next W01", sans-serif;
  -webkit-transition: all 1s ease-in-out;
  transition: all 1s ease-in-out;
  box-sizing: border-box;
}

.label.show {
  visibility: visible;
  opacity: 1;
}

.top .label:first-child {
  color: #d85b74;
}

.top .label:last-child {
  padding-right: 20%;
}

.game {
  width: 100%;
  height: 100%;
  margin: auto;
  position: absolute;
  top: 0px;
  left: 0px;
  bottom: 0px;
  right: 0px;
  overflow: hidden;
  cursor: inherit;
}

@media only screen and (max-device-width : 767px) { 
  .game { 
    height:160%;
  	/* -webkit-transform: translateY(-250px); 
  	transform: translateY(-250px); */
    top:-10px;
     -webkit-transform: scale(0.7,0.65);
    transform: scale(0.7,0.65); 
  }

}

@media only screen and (max-device-width : 767px) and (orientation : portrait) { 
	.game{
	display: none;
	} }


.slide {
  visibility: hidden;
  opacity: 0;
  position: absolute;
  z-index: 1;
  width: 100%;
  height: 100%;
  text-align: center;

  -webkit-transition: all .1s ease-in-out;
  transition: all .1s ease-in-out;
}

.slide.visible {
  visibility: visible;
  opacity: 1;
}

.slide .illustration {
  margin-left: auto;
  margin-right: auto;
  display: inline-block;
  position: absolute;
  left: 0;
  right: 0;
  top: -70px;
}

.slide.visible .illustration img,
.slide.visible .illustration .numberLeft {
  -webkit-animation: fadeUp .5s ease-out forwards;
  animation: fadeUp .5s ease-out forwards;
  -webkit-transform: translate3d(-50%,-50%,0);
  transform: translate3d(-50%,-50%,0);
  opacity: 0;
}

.slide.visible .example-biomarker:first-child {
  margin-left: 0;
}

.slide.visible .example-biomarker:nth-child(2) {
  -webkit-animation: fadeUp .5s ease-out forwards
  animation: fadeUp .5s ease-out forwards;
  -webkit-animation-delay: .1s;
  animation-delay: .1s, .1s;
}

.slide.visible .example-biomarker:last-child {
  -webkit-animation-delay: .2s;
  animation-delay: .2s;
}

.slide .title,
.help-screen .title {
  margin: 2rem auto;
  width: 60%;
  font-size: 2rem;
  line-height: 2.5rem;
  position: relative;
  z-index: 1;
}

.button {
  font-size: 2rem;
  cursor: pointer;
  margin: 0 auto;
  display: inline-block;
  padding: 1rem 3rem;
  border-radius: 2px;
}

.slideshow .page-markers {
  margin-top: 45px;
}

.slideshow .page-markers .marker {
  display: inline-block;
  width: 10px;
  height: 10px;
  border-radius: 5px;
  margin-left: 5px;
  margin-right: 5px;
}

.wrapper {
  position: relative;
  top: 50%;

  -webkit-transform: translateY(-50%);
  transform: translateY(-50%);
}

.slideshow .page-markers .on {
  background-color: white;
}

.slideshow .page-markers .off {
  background-color: rgba(0,0,0,0.2);
  cursor: pointer;
}

.slideshow .page-markers .off:hover {
  background-color: rgba(0,0,0,0.3);
}

.slideshow .controls .next, .slideshow .controls .prev {
  position: absolute;
  padding: 20px;
  font-size: 1.5rem;
  text-align: center;
  cursor: pointer;
  top: 0;

  -webkit-transition: all .05s ease-in-out;
  transition: all .05s ease-in-out;
}

.slideshow .controls .prev:hover {
  -webkit-transform: translateX(-5px);
  transform: translateX(-5px);
}

.slideshow .controls .next:hover {
  -webkit-transform: translateX(5px);
  transform: translateX(5px);
}

.slideshow .controls .next:active, .slideshow .controls .prev:active {
  color: rgba(0,0,0,0.5);
}

.slideshow .controls .next {
  right: 32px;
}

.slideshow .controls .prev {
  left: 32px;
}

.slideshow .controls .next::before {
  content: url('media/med_next.png');
}

.slideshow .controls .prev::before {
  content: url('media/med_prev.png');
}

.slideshow .slide {
  z-index: 1;
  position: absolute;
}

.slideshow .slide0 {
  background-image: -webkit-radial-gradient(center, ellipse cover, rgba(243,237,228,.93) 50%,rgba(243,237,228,0) 100%);
  background-image: -webkit-gradient(radial, center center, 0px, center center, 100%, color-stop(50%,rgba(243,237,228,0.93)), color-stop(100%,rgba(243,237,228,0)));
  background-image: -moz-radial-gradient(center, ellipse cover, rgba(243,237,228,0.93) 50%, rgba(243,237,228,0) 100%);
  background-image: radial-gradient(ellipse at center, rgba(243,237,228,0.93) 50%,rgba(243,237,228,0) 100%);
  background-image: -ms-radial-gradient(center, ellipse cover, rgba(243,237,228,0.93) 50%,rgba(243,237,228,0) 100%);
  color: #64626e;
}

.slideshow .slide0 .title {
  margin-top: 100px;
}

.slideshow .slide0 .title .focus {
  margin-top: 3px;
  font-family: "Trade Gothic Next W01", sans-serif;
  font-size: 2.5rem;
}

.slideshow .slide0 .body {
  margin: 30px auto 0;
  font-size: 1.2rem;
  line-height: 1.8rem;
  max-width: 470px;
}

.slideshow .slide0 .next {
  width: 80px;
  height: 80px;
  background-color: #f5cd7d;
  border-radius: 40px;
  margin: 40px auto;
  background-image: url('media/med_next.png');
  background-repeat: no-repeat;
  background-position: 55% 50%;
  background-size: 20px;
  cursor: pointer;

  -webkit-transition: all .05s ease-in-out;
  transition: all .05s ease-in-out;
}

.slideshow .slide0 .next:hover  {
  background-color: rgba(244,205,125,.85);
}

.slideshow .slide0 .next:active  {
  background-color: #eec574;
}

.slideshow .slide0 .cells {
  position: absolute;
  top: 160px;
  left: 0;
  right: 0;
  max-width: 950px;
  width: 100%;
  margin-left: auto;
  margin-right: auto;
}

.slideshow .slide0 .immune-cell, .slideshow .slide0 .healthy-cell {
  width: 200px;
  height: 200px;
}

.slideshow .slide0 .immune-cell {
  float: left;
  animation: wiggle 10s ease-in-out infinite;
  -moz-animation: wiggle 10s ease-in-out infinite;
  -webkit-animation: wiggle 10s ease-in-out infinite;
  -ms-animation: wiggle 10s ease-in-out infinite;
}

.slideshow .slide0 .healthy-cell {
  float: right;
  animation: backwards-wiggle 10s ease-in-out infinite;
  -moz-animation: backwards-wiggle 10s ease-in-out infinite;
  -webkit-animation: backwards-wiggle 10s ease-in-out infinite;
  -ms-animation: backwards-wiggle 10s ease-in-out infinite;
}

.slideshow .slide1 {
  background-color: rgba(236,168,184,0.9);
}

.slideshow .slide1 strong {
  color: #c94062;
}

.slideshow .slide2 {
  background-color: rgba(106,187,219,0.9);
}

.slideshow .slide3 {
  background-color: rgba(155,210,168,0.9);
}

.slideshow .slide3 strong {
  color: #4bab74;
}

.slideshow .slide2 .example-biomarker {
  margin: 0 20px;
}

.slideshow .slide2 .auto-immune {
  border-bottom: 2px dashed rgba(255,255,255,.5);
}

.slideshow .slide2 .nowrap {
  white-space: nowrap;
}

.slideshow .slide3 .numberLeft {
  background-color: #4bab74;
  display: inline-block;
  margin-left: auto;
  margin-right: auto;
  font-size: 3rem;
  border-radius: 2px;
  padding: 1rem 2rem;
  font-family: "TradeGothicNextW01-Bold 693229", sans-serif;
}

.slideshow .slide3 .footer-controls {
  position: absolute;
  left: 0;
  right: 0;
  bottom: -110px;
}

.slideshow .slide3 .begin-button {
  background-color: #4bab74;
}

.slideshow .slide3 .begin-button:hover {
  background-color: rgba(79,180,120,.95);
}

.slideshow .slide3 .begin-button:active {
  background-color: #419565;
}

.help-icon {
  display: none;
  position: absolute;
  z-index: 3;
  left: 25px;
  bottom: 20px;
  background-color: rgba(0,0,0,0.1);
  padding: .7rem 1rem;
  border-radius: 2px;
  cursor: pointer;
}

.help-icon img {
  width: 15px;
}

.help-icon:hover {
  background-color: rgba(0, 0, 0, 0.12);
}

.help-icon.show {
  display: block;
}

.help-screen {
  visibility: hidden;
  z-index: 3;
  position: absolute;
  height: 100%;
  width: 100%;
  text-align: center;
  color: rgba(100, 98, 110, 0.8);
  background-color: rgba(243,237,228,0.93);
  opacity: 0;
  
  -webkit-transition: all .2s linear;
  transition: all .2s linear;
}

.help-screen .title,
.help-screen .button {
  font-size: 1.8rem;
}

.help-screen strong {
  color: #4bab74;
}

.help-screen.show {
  visibility: visible;
  opacity: 1.0;
  transition-delay: 0s;
}

.help-screen .close-x {
  display: block;
  position: absolute;
  top: 0;
  right: 0;
  width: 30px;
  height: 30px;
  padding: 40px;
  opacity: .6;
  cursor: pointer;
  background: url("media/close_icon.png") no-repeat center;
  background-size: 30px;
  z-index: 4;
}

.help-screen .close-x:hover {
  opacity: 1;
}

.help-screen .cell-table {
  margin: 0px auto 30px;
}

.help-screen .cell-table td {
  width: 225px;
  text-align: center;
}

.help-screen .footer-controls {
  margin-top: 50px;
}

.help-screen .close-button {
  color: white;
  background-color: rgba(100,98,110,.6);
}

.help-screen .close-button:hover {
  background-color: rgba(100,98,110,.55);
}

.help-screen .restart-button {
  opacity: .8;
}

.help-screen .restart-button:hover {
  opacity: 1;
}

.molecule-toolbar {
  visibility: hidden;
  opacity: 0;
  z-index: 1;
  position: absolute;
  right: 30px;
  top: 50%;

  -webkit-transform: translateY(-50%);
  transform: translateY(-50%);

  -webkit-transition: all .2s linear;
  transition: all .2s linear;
}

.molecule-toolbar.show {
  visibility: visible;
  opacity: 1;
  transition-delay: 0s;
}

.molecule-toolbar .main .button, .molecule-toolbar .main .numberLeft {
  margin-top: 1rem;
  margin-left: auto;
  margin-right: auto;
  text-align: center;
  border-radius: 2px;
  font-family: "TradeGothicNextW01-Bold 693229", sans-serif;
}

.molecule-toolbar .main .button {
  display: block;
  cursor: pointer;
  background-color: rgba(0, 0, 0, 0.1);
}

.molecule-toolbar .main .button:hover {
  background-color: rgba(0, 0, 0, 0.12);
}

.molecule-toolbar .main .button:not(.disabled):active {
  background-color: rgba(0, 0, 0, 0.15);
}

.molecule-toolbar .main .button {
  background-position: center;
  background-repeat: no-repeat;
  background-size: 3rem;
  padding: 3rem;
}

.molecule-toolbar .main .molecule1 {
  background-image: url("media/antibody_1.png");
}

.molecule-toolbar .main .molecule2 {
  background-image: url("media/antibody_2.png");
}

.molecule-toolbar .main .molecule3 {
  background-image: url("media/antibody_3.png");
  background-size: 2.5rem;
}

.molecule-toolbar .main .button.on {
  background-color: rgba(100,98,110,0.8);
}

.molecule-toolbar .main .button.disabled {
  cursor: auto;
  opacity: 0.2;
}

.molecule-toolbar .status .numberLeft {
  background-color: #7dc99e;
  font-size: 3.5rem;
  padding: 1rem 0.5rem;
}

.molecule-toolbar .status .description {
  margin-top: 10px;
  color: #7dc99e;
  font-size: 1rem;
  font-weight: bold;
  text-align: center;
}

.bottom {
  position: absolute;
  bottom: 0px;
  width: 100%;
  z-index: 1;
}

.confirm {
  border-radius: 2px 2px 0 0;
  margin: 0 auto;
  text-align: center;
  font-size: 1.2rem;
  width: 510px;
  padding: 25px;
  padding-right: 15px;

  -webkit-transform: translateY(100%);
  transform: translateY(100%);

  -webkit-transition: all .05s ease-out;
  transition: all .05s ease-out;
}

.confirm.a {
  background-color: #EBBC68;
}

.confirm.b {
  background-color: #ef8a62;
}

.confirm.c {
  background-color: #a97cae;
}

.confirm .yes, .confirm .no {
  padding: 10px 30px;
  margin-left: 10px;
  cursor: pointer;
  border-radius: 2px;
}

.confirm .yes {
  background-color: rgba(0,0,0,0.1);
  padding-left: 27px;
  margin-left: 25px;
}

.confirm .yes:hover {
  background-color: rgba(0,0,0,0.2);
}

.confirm .no:hover {
  background-color: rgba(0,0,0,0.05);
}

.confirm.show {
  -webkit-transform: translateY(0);
  transform: translateY(0);
}

.confirm .button {
  border-radius: 2px;
  width: 32px;
  height: 32px;
  float: left;
  margin-left: 16px;
  margin-top: 16px;
  margin-right: 8px;
  cursor: pointer;
}

.win-condition, .lose-condition {
  visibility: hidden;
  opacity: 0;
  z-index: 1;
  position: absolute;
  height: 100%;
  width: 100%;
  text-align: center;
  background-color: white;
  transition: visibility 0s linear .5s, opacity .5s linear;
  -webkit-transition: visibility 0s linear .5s, opacity .5s linear;
  -moz-transition: visibility 0s linear .5s, opacity .5s linear;
  -ms-transition: visibility 0s linear .5s, opacity .5s linear;
}

.win-condition.show, .lose-condition.show {
  visibility: visible;
  opacity: 1.0;
  transition-delay: 0s;
}

.win-condition .footer-controls, .lose-condition .footer-controls {
  margin-top: 54px;
}

.win-condition {
  background-color: rgba(155,210,168,0.9);
}

.win-condition .play-again {
  background-color: #4bab74;
}

.win-condition .play-again:hover {
  background-color: #77c598;
}

.win-condition .play-again:active {
  background-color: #419565;
}

.win-condition .healthy-count {
  color: #4bab74;
}

.lose-condition {
  background-color: rgba(236,168,184,0.9);
}

.win-condition .body, .lose-condition .body {
  font-size: 2rem;
  line-height: 130%;
  position: relative;
  top: 50%;
  width: 70%;
  margin: 0 auto;

  -webkit-transform: translate3d(0,-50%,0);
  transform: translate3d(0,-50%,0);
}

.lose-condition .auto-immune {
  color: #d95b74;
}

.lose-condition .retry {
  background-color: #d95b74;
}

.lose-condition .retry:hover {
  background-color: #e0657d;
}

.lose-condition .retry:active {
  background-color: #c74c64;
}

.lose-condition .view-instructions {
  width: auto;
  padding-right: 30px;
  padding-left: 30px;
  color: rgba(255,255,255,.8);
}

.lose-condition .view-instructions:hover {
  color: rgba(255,255,255,1);
}

.lose-condition .footer-controls div {
  display: inline-block;
}

@font-face {
  font-family: "TradeGothicNextW01-Bold 693229";
  src: url("media/fonts/678017fc-bfca-4daa-a38a-b0f41bada5e7-.eot#iefix");
  src: url("media/fonts/678017fc-bfca-4daa-a38a-b0f41bada5e7-.eot#iefix") format("eot"), url("media/fonts/4d16ea6c-033a-41b1-8326-56a1d7392d5f.woff") format("woff"), url("media/fonts/573b39c2-10f7-4b72-a656-89a329b76560.ttf") format("truetype"), url("media/fonts/d079b7e1-7489-4f6d-b4c9-536742085cff.svg#d079b7e1-7489-4f6d-b4c9-536742085cff") format("svg");
}
@font-face {
  font-family: "TradeGothicNextW01-Bold 693232";
  src: url("media/fonts/62cdf702-7113-4955-9b29-d803174650c7-.eot#iefix");
  src: url("media/fonts/62cdf702-7113-4955-9b29-d803174650c7-.eot#iefix") format("eot"), url("media/fonts/a43fe47f-004d-4b6d-9a72-23de9e08f66e.woff") format("woff"), url("media/fonts/de22c287-e0dc-4287-8a0e-3f68a8788330.ttf") format("truetype"), url("media/fonts/d7c320de-0c26-418a-b1d2-ef600169db34.svg#d7c320de-0c26-418a-b1d2-ef600169db34") format("svg");
}
@font-face {
  font-family: "TradeGothicNextW01-Cond";
  src: url("media/fonts/5be4a815-5a22-4a8b-8a38-10467be39d2e-.eot#iefix");
  src: url("media/fonts/5be4a815-5a22-4a8b-8a38-10467be39d2e-.eot#iefix") format("eot"), url("media/fonts/eb20bf3e-7a5c-4c98-8bc5-f38c1b3dd9f2.woff") format("woff"), url("media/fonts/bbd9ed4b-21d6-4a35-a3eb-176c31258e03.ttf") format("truetype"), url("media/fonts/2b33a704-0f65-4c4c-94d0-2bd00c0151af.svg#2b33a704-0f65-4c4c-94d0-2bd00c0151af") format("svg");
}
@font-face {
  font-family: "TradeGothicNextW01-Ligh 693250";
  src: url("media/fonts/c22083eb-f768-467a-8736-cd9014be4e4f-.eot#iefix");
  src: url("media/fonts/c22083eb-f768-467a-8736-cd9014be4e4f-.eot#iefix") format("eot"), url("media/fonts/1e25c4c8-80d6-44ba-bc21-51daaa0cd556.woff") format("woff"), url("media/fonts/41757792-b783-4a47-9e47-62f4fc3d2ea6.ttf") format("truetype"), url("media/fonts/d30fef5b-e7a0-444c-8fbf-629dbf84f4f8.svg#d30fef5b-e7a0-444c-8fbf-629dbf84f4f8") format("svg");
}
@font-face {
  font-family: "Trade Gothic Next W01";
  src: url("media/fonts/8a6c3750-4927-4649-9dac-87049f5e9700-.eot#iefix");
  src: url("media/fonts/8a6c3750-4927-4649-9dac-87049f5e9700-.eot#iefix") format("eot"), url("media/fonts/57625f96-ca80-4602-9644-ec1803cb3ba3.woff") format("woff"), url("media/fonts/6618d500-1727-4334-878e-1c4b95192f42.ttf") format("truetype"), url("media/fonts/01ebe944-ca6c-41db-a3ba-b7e2a90536d9.svg#01ebe944-ca6c-41db-a3ba-b7e2a90536d9") format("svg");
}

@keyframes wiggle {
  0% {
    transform: translateX(0);
  }

  50% {
    transform: translate3d(-25px, -25px, 0);
  }

  100% {
    transform: translateX(webkit);
  }

}

@-webkit-keyframes wiggle {
  0% {
    -webkit-transform: translateX(0);
  }

  50% {
    -webkit-transform: translate3d(-25px, -25px, 0);
  }

  100% {
    -webkit-transform: translateX(0);
  }
}


@-moz-keyframes wiggle {
  0% {
    -moz-transform: translateX(0);
  }

  50% {
    -moz-transform: translate3d(-25px, -25px, 0);
  }

  100% {
    -moz-transform: translateX(0);
  }
}


@-ms-keyframes wiggle {
  0% {
    -ms-transform: translateX(0);
  }

  50% {
    -ms-transform: translate3d(-25px, -25px, 0);
  }

  100% {
    -ms-transform: translateX(0);
  }
}

@keyframes backwards-wiggle {
  0% {
    transform: translateX(0);
  }

  50% {
    transform: translate3d(25px, 30px, 0);
  }

  100% {
    transform: translateX(webkit);
  }

}

@-webkit-keyframes backwards-wiggle {
  0% {
    -webkit-transform: translateX(0);
  }

  50% {
      -webkit-transform: translate3d(25px, 30px, 0);
  }

  100% {
    -webkit-transform: translateX(0);
  }
}

@-moz-keyframes backwards-wiggle {
  0% {
    -moz-transform: translateX(0);
  }

  50% {
      -moz-transform: translate3d(-25px, 30px, 0);
  }

  100% {
    -moz-transform: translateX(0);
  }
}

@-ms-keyframes backwards-wiggle {
  0% {
    -ms-transform: translateX(0);
  }

  50% {
    -ms-transform: translate3d(-25px, 30px, 0);
  }

  100% {
    -ms-transform: translateX(0);
  }
}

.tooltip[data-tooltip] {
  position: relative;
  text-decoration: none;
  color: inherit;
  cursor: pointer;
}

.tooltip[data-tooltip]::before,
.tooltip[data-tooltip]::after {
  position: absolute;
  display: none;
}

.tooltip[data-tooltip]::before {
  content: attr(data-tooltip);
  background: #50AAD7;
  color: #fff;
  font-size: 20px;
  padding: 20px;
  border-radius: 2px;
  text-decoration: none;
  width: 500px;
  margin-left: -200px;
}

.tooltip[data-tooltip]::after {
  width: 0;
  height: 0;
  border: 10px solid transparent;
  content: '';
}

.tooltip[data-tooltip].open::before,
.tooltip[data-tooltip].open::after {
  display: block;
}


.tooltip[data-tooltip][data-placement="bottom"]::before {
  top: 100%;
  left: 0;
  margin-top: 20px;
}

.tooltip[data-tooltip][data-placement="bottom"]::after {
  border-bottom-color: #50AAD7;
  border-top: none;
  top: 100%;
  left: 50%;
  margin-left: -5px;
  margin-top: 10px;
}



@keyframes fadeUp {
  0% {
    opacity: 0;
    transform: translateY(0);
  }
  
  60% {
    opacity: 1;
    transform: translateY(-80%);
  }
  
  100% {
    opacity: 1;
    transform: translateY(-70%);
  }
}

@-webkit-keyframes fadeUp {
  0% {
    opacity: 0;
    -webkit-transform: translateY(0);
  }
  
  60% {
    opacity: 1;
    -webkit-transform: translateY(-80%);
  }
  
  100% {
    opacity: 1;
    -webkit-transform: translateY(-70%);
  }
}

@keyframes spinClockwise {
  0% {
    transform: translateY(-70%) rotate(0);
  }
  
  100% {
    transform: translateY(-70%) rotate(360deg);
  }
}

@-webkit-keyframes spinClockwise {
  0% {
    -webkit-transform: translateY(-70%) rotate(0);
  }
  
  100% {
    -webkit-transform: translateY(-70%) rotate(360deg);
  }
}

@keyframes spinCounter {
  0% {
    transform: translateY(-70%) rotate(0);
  }
  
  100% {
    transform: translateY(-70%) rotate(-360deg);
  }
}

@-webkit-keyframes spinCounter {
  0% {
    -webkit-transform: translateY(-70%) rotate(0);
  }
  
  100% {
    -webkit-transform: translateY(-70%) rotate(-360deg);
  }
}

@media all and (max-width: 800px) {

  html {
    font-size: 12px;
  }

  .slide0 .body {
    width: 50%;
  }
}