Scientist, Small Molecule Pharmaceutics, Genentech Research

South San Francisco, California
United States

Job ID: 00453071

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The Position

We are seeking a Scientist to support drug discovery in the Department of Small Molecule Pharmaceutics at Genentech. The primary responsibilities for this role extend from formulation and pharmaceutics support from early stage research to late stage research, IND-enabling safety studies, and informing development strategy for clinical formulation. This person will primarily be responsible for pharmaceutical profiling and drug delivery approaches during preclinical assessment of novel small molecule therapeutics for unmet medical needs.

The successful candidate is expected to:

  • Drive scientific and technical innovation collaboratively with other members of Discovery teams and within Small Molecule Pharmaceutical Sciences.
  • Focus on selection, profiling and advancing small molecule clinical candidates in a scientifically rigorous, phase-appropriate manner
  • Develop and execute pre-formulation and preclinical formulation strategies based on strong scientific rationale and pharmaceutical/biopharmaceutical properties of molecules for one or more projects
  • Based on preclinical knowledge, identify potential risks during clinical formulation development.
  • Leverage preclinical knowledge, participate in key decisions such as physical form selection and clinical formulation design
  • Have a proven track record of publication in high quality scientific journals
  • Participate and thrive in an interactive, collaborative, team-oriented culture, interfacing with discovery and early development functions


Who You Are

A Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering or related fields with 3-8 years’ experience in the pharmaceutical industry. Knowledge and expertise in the interplay between molecular physicochemical properties, absorption processes, and pharmacokinetic/pharmacodynamic (PK/PD) relationships with formulation modality is required. Experience in working within the drug discovery space is highly desired. Additionally, experience in alternative therapeutic modalities (such as peptides, etc.) and drug delivery technologies (such as inhalation, ocular, topical, etc.) is highly valued.

The successful candidate must have excellent communication skills, interpersonal skills,
and problem-solving skills, as well as demonstrate the ability to plan, design, implement and analyze laboratory experiments to advance projects and guide formulation selection and development.


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Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


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