Associate Scientist /Scientist, DMPK

South San Francisco
California, United States of America


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The Position

The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated individual who will be involved in the in vitro to in vivo translation of data in the non-clinical space.   This position will support our continued efforts to address gaps in in vitro – in vivo correlation and extrapolation (IVIVC and IVIVE).   A significant portion (? 50 %) of the time of this position is expected to be spent hands-on in the lab.  The expectation is that the individual will be involved in:

  • Design and execution of in vitro studies
  • Collaboration with scientists within and outside DMPK to support projects
  • DMPK data analysis and modeling
  • Model building

Requirements:  A PhD degree specializing in pharmacokinetics and/or drug metabolism or other relevant fields.  Direct experience with common in vitro ADME systems. A strong understanding of in vitro and in vivo DMPK principles.

Desirable Good organizational, collaboration, communication skills and flexibility are important assets.  0 – 4 years previous pharmaceutical industry experience with experience in drug discovery and candidate selection. Familiarity with PK/PD and PBPK basic methodology and principles. Familiarity with commonly encountered modeling and simulation packages (e.g. WinNonlin, Simcyp, Gastroplus, ADAPT, SAAMII ).  In addition, familiarity with software packages such as MATLAB, SIMBIOLOGY, Python, R or other similar programs is highly desirable.

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Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.


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