Sr. Principal Product Manager - Data Management, Personalized Healthcare IT (Imaging)

South San Francisco
California, United States of America

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The Position

The power of data at scale has transformed almost every industry, personalizing experiences in many aspects of our lives. Yet in healthcare we’ve only scratched the surface. At Genentech and Roche we are accelerating the use of data insights and digital technologies to make significant strides to reach the full potential of personalized healthcare. We are seeking mission-driven, ardent, self-starting, creative individuals to join us in this effort.  

The Sr. Principal Product Manager will have end-to-end ownership of the PHC (Personalized Healthcare) Global Data Management Platform. This role will be part of the Pharma PHC IT/Technology Team that provides global technology solutions to enable the Pharma PHC Vision and Strategy. The Sr. Principal Product Manager will partner with senior stakeholders in multiple groups to design, develop and operate the PHC Global Data Management Platform for Roche/Genentech’s current and future PHC data management needs. The PHC Global Data Management Platform will manage large scale Global Scientific Datasets including Omics, Imaging, Digital, EHR modalities. This person will work very closely with key stakeholders in the PHC Center of Excellence to coordinate technology strategy with the PHC COE strategy and portfolio.

We expect the Sr. Principal Product Manager to be a passionate business and product advocate within IT, with proven analytical capabilities. The Sr.Principal Product Manager must be an effective negotiator, leader and communicator in working with Roche/Genentech’s multiple business units as well as with internal IT cross-functional teams. The ideal candidate will be a self-starter with a passion for data management products, a high level of flexibility, commitment, and a sense of humor. The Sr. Principal Product Manager will join our diverse community of smart, fun, wholehearted, and engaged informatics professionals from various functional areas. This person will share our community values of passion, courage, integrity, and gratitude -- all in service of our mission, “doing now what patients need next.”



As Sr. Principal Product Manager on the PHC Pharma IT/Technology team, you will:

  • Partner closely with key stakeholders from PHC Center of Excellence, Research and Early Development teams (REDs), Product Development (PD) and Commercial business groups, and corresponding Pharma IT Groups and Global Infrastructure and Solutions (GIS)

  • Influence senior leaders across Roche and communicate PHC Global Data Management vision, strategy, goals, status, and impact

  • Develop and document the Platform Vision and Strategy – Including all aspects to future roadmap, investment, innovation and experimentation.

  • Collaborate with key stakeholders to gather detailed requirements and use cases for various data modalities, including Imaging, ‘Omics, Digital Health, and Real World Data (RWD).

  • Transform detailed requirements and use cases into solution capabilities and map those capabilities to various vendor and internal technology platforms to inform architecture and solution design.

  • Lead Implementation - Work with business, development/engineering & infrastructure teams to architect, design, prototype, develop the platform and ensure product deliverables meet expectations.

  • Lead Rollout - Work with highly cross-functional teams to rollout the platform into various business groups and conduct/manage user training.

  • Lead Operations – Including monitoring and response to customer feedback, continuous improvement and business growth

  • Have a broad knowledge and leverage the technical capabilities of the internal teams and external technology providers and vendors.

  • Help identify and manage third party vendor relationships and collaborations.

  • Conduct market assessments and to identify new capabilities for existing and future business needs.

  • Collaborate with PHC Portfolio Strategy and Architecture team to contribute to the PHC IT/technology roadmap


  • Bachelor’s degree in Biology, Computer Science, Mathematics, Electrical Engineering, Information Systems or related field; Master/PHD in Business, Mathematics, Science, or Computer Science preferred

  • 10+ years experience leading technical products, applications and analytical systems

  • 3+ years of people management and product management experience

  • Demonstrated experience with full life-cycle product management: problem definition and solution discovery, stakeholder buy-in, validation, launch, and ongoing operations

  • Strong Experience in designing and implementing high available and high scalable big data systems; 3+ years of experience in leading implementation of high scalable data management systems preferred

  • Proven Domain Experience with and understanding of two or more the following data domains: Genomics, Imaging, Digital Health, Clinical Trials, Real World Data including EHR

  • Solid understanding of AWS and/or similar cloud stacks

  • Experience with data management lifecycle – Data Quality, Information LifeCycle, Data Governance, Analytics, Master Data Management

  • Excellent communication (written and oral) and presentation skills; solid business acumen; well-honed influencing skills are essential.

  • Self-motivated and team-oriented; able to work both autonomously and effectively as part of a geographically dispersed team

  • Proven understanding with technologies like Spark, Hadoop, Flink, Cassandra, Elastic Search, TensorFlow and other big data & AI/ML technologies preferred


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

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