I2O Portfolio Lead

South San Francisco
California, United States of America

Return to Search Results

The Position

The Position

Manager / Sr. Manager, Portfolio Lead, Pipeline & Portfolio Planning (PPP) Late Stage in Immunology, Infectious Disease, and Ophthalmology (I2O)

The PPP Portfolio Lead plays a critical role in broadly influencing product development and advancing treatments for Roche patients. The individuals partner with lifecycle leaders and senior management in I2O Therapeutic Area (TA) to make critical product development and portfolio decisions by:

  • Advising Therapeutic Area Heads (TAH), Franchise Heads (FH), life cycle leaders (LCL) on significant development decisions and lifecycle plans

  • Performing business case assessments for development decisions, including valuation of various options to be considered by the lifecycle team

  • Providing portfolio insights and analytics to enable strategic discussions, scenario planning, decision and trade-off analyses for investment options and to ensure alignment of lifecycle plans with portfolio priorities and strategy

  • Supporting Disease Area Strategy and lifecycle strategy projects, both in ‘where to play’ decisions (e.g. market prioritization, product market selection) and ‘how to win’ decisions (e.g. clinical strategy, diagnostic strategy, access strategy)

  • Playing a critical role in broadly influencing product development and advancing treatments for I2O patients

  • Supporting PPP practice building activities to ensure robust and state-of-the-art portfolio management tools/methodologies


Key responsibilities include, but not limit to:

  • Serve as an active member on multiple Lifecycle Teams (LCT) and Disease Area Strategy (DAS) teams to support the development of externally competitive and internally aligned strategies

  • Advise on prioritization of development and strategic options with clear perspectives on strategic context, value proposition, key risks, contingency plans, tradeoffs, and provide a formal recommendation to teams

  • Facilitate Life Cycle Teams engagement with the Late Stage decision makers (LSPC and TAHs) by identifying critical business questions, framing the solutions, and simplifying the decision processes

  • Partner with Roche Partnering and early stage (gRED and pRED) PPP Lead to develop understanding of partnering activities and Roche pipeline across all development stages.  Support g/pRED teams for timely and smooth asset transition from early to late stage

  • Represent PPP in leading cross-functional initiatives and processes, including executive presentations and strategy development

Who you are

In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring the best to the business and to their personal lives.


  • Advanced degree in science, engineering, business or a related field

  • Experience or background in immunology, infectious diseases and/or ophthalmology is a plus

  • At least 5 years of experience in biotech, pharmaceuticals or a related field in business related functions.

  • Experience in strategic planning and analytics is strongly desirable.

  • Ideal candidate will have 3-5 years of experience in marketing, market planning, business development, management consulting, or investment banking

  • Evidence of strong strategic thinking, communication, analytics/modeling, planning and organizational skills required. Interviews will include case studies.

  • Knowledge of drug development and familiarity with industry economic benchmarks.

  • Ability to influence senior leaders on critical decisions.

  • Experience successfully leading strategic initiatives.

  • Ability to simplify decision-making via well-articulated frameworks.

  • Ability to lead and facilitate cross functional teams.

  • Ability to innovate.

  • Ability to travel 10-15% (domestic and international)

Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

Return to Search Results