Scientist, Oncology Biomarker Development

South San Francisco
California, United States of America

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The Position

The Position:

We seek a highly motivated Scientist within Development Sciences to support biomarker and diagnostic development efforts focusing on Genentech's Oncology pipeline. The incumbent will apply advanced bioinformatics and data analysis skills in collaboration with a group of biomarker scientists to execute on predictive and pharmacodynamic biomarker, and companion diagnostic strategies for programs in clinical development.

For this particular position, a strong background in cancer biology and bioinformatics or biostatistics, evidenced by peer reviewed publications in top tier journals, would be an important asset. The successful candidate is expected to effectively interact with cross functional teams; analyze data supporting innovative clinical development programs and publications focused on biomarker or disease research; interact with key collaborators and investigators; and promote collaborative efforts to advance biomarker sciences.

As a Scientist, you are expected to:

  • Manage and support analysis of large clinical biomarker datasets including NGS-based DNA and RNA testing
  • Effectively manage scientific collaborations, both internal and external
  • Drive scientific and technical innovation collaboratively with other members of the department
  • Support development and execution of exploratory biomarker and companion diagnostic strategies for multiple projects
  • Support publications in high quality scientific, technical or medical journals
  • Represent the biomarker team externally through interactions with our key investigators
  • Participate and thrive in an interactive, team oriented culture

Who You Are

  • PhD degree in a relevant scientific field (e.g., molecular biology, cancer biology, genomics, or bioinformatics)
  • Minimum of 2 years postdoctoral experience in basic or translational research either in an academic or industry setting
  • Strong bioinformatics programming skills (e.g., using R or Python) and familiarity with the Unix operating system.  Experience with Bioconductor is preferred.
  • Experience analyzing and interpreting high throughput genomic data, especially whole exome, targeted NGS, and whole transcriptome sequencing, is highly desired
  • NGS assay or platform development expertise, particularly with clinical sequencing applications, would be highly beneficial
  • Experience in clinical drug development is beneficial, including understanding of critical development functions, e.g., biomarker development, operations, and biostatistics.
  • Knowledge and understanding of current methods being used to assess tumor biology in the clinical setting, and familiarity with systems biology tools would be advantageous


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

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