Scientist, Oncology Biomarker Development

South San Francisco
California, United States of America

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The Position

We are seeking a highly motivated Scientist to lead biomarker efforts to support Cancer Immunotherapy drug development strategies. Previous experience in biomarkers, and a strong scientific background in cancer immunotherapy, immunology, and/or oncology is highly desirable. The successful candidate is expected to effectively interact with cross functional teams and thrive in an interactive, team-oriented culture, to envision and execute biomarker plans, to support or lead clinical and/or reverse translational research publications, and to promote collaborative efforts aimed to push novel biomarker science and/or innovative endpoints and technologies forward. We are looking for a candidate with excellent verbal and presentation skills. The incumbent is expected to contribute to drug development and to grow over time into externally recognized leader in translational science who influence the field of personalized medicine in oncology.

Primary responsibilities:

  • Provide exceptional scientific leadership to peers in OBD and assigned project teams (including clinical researchers, discovery scientists, bioinformatics scientists)
  • Design, implement and lead the biomarker strategy for Genentech’s cancer immunotherapy (CIT) products in multiple programs
  • Drive and manage scientific collaborations, both internal and external
  • Lead scientific initiative efforts aimed to incorporate novel biomarker endpoints in clinical trials.
  • Generate novel biological insights based clinic biomarker reverse translation research into specific tumor indications.
  • Support publications in high quality scientific, technical or medical journals
  • Represent OBD externally through interactions with key investigators and regulatory entities


  • PhD, MD, or PhD/MD degree in a relevant scientific field (e.g. immunology, molecular biology, cancer genetics, cancer biology, molecular oncology).
  • Minimum of 5-10 years post-doctoral experience in basic or translational research either in an academic and/or industry
  • Experience in clinical drug development and biomarkers is beneficial, including basic or advanced understanding of critical development functions, e.g. Clinical Pharmacology, Regulatory, Safety, Operations, Biostatistics, etc.
  • Solid record of publications in peer review scientific journals
  • Be able to distill complex issues and clearly articulate solutions
  • Ability to collaborate, lead, influence and motivate others.
  • Ability to demonstrate effectiveness and growth in a fast-paced and dynamic environment
  • Outstanding presentation and communication skills



Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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