Associate Scientist, Biomarker Mass Spectrometry Laboratory

South San Francisco
California, United States of America

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The Position

We are seeking a highly motivated laboratory-based scientist to join the OMNI Biomarker Development group within Development Sciences. Our group is responsible for designing and implementing biomarker assays using mass spectrometry to support programs in clinical development at Genentech in the disease areas of Immunology, Inflammation and Autoimmune Diseases, Ophthalmology, Metabolism, and Neuroscience.  

As a key member of the biomarker mass spectrometry laboratory, the ideal candidate will utilize mass spectrometry to explore novel biomarker hypotheses and support clinical development. Expertise in developing quantitative mass spectrometry assays, experience in clinical sample processing from biological matrices and a strong analytical background is required. Hands-on experience with small or large molecule sample preparation and LC and MS instrumentation is also required.

  • PhD in Analytical Chemistry, Biochemistry, or Biotechnology
  • Minimum of 4 years of hands-on experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) (SCIEX and Thermo instruments), and have strong troubleshooting capabilities
  • Strong analytical background with fundamentals in quantitative assay development and assay evaluation
  • Knowledge of sample preparation techniques for analysis of drugs, biomarkers and other mediators from biological fluids (e.g. plasma, serum, CSF, urine)
  • Demonstrated expertise in the quantitative analysis of compounds from biological matrices, especially using HPLC and HPLC-MS techniques
  • Experience developing quantitative MS techniques (e.g. SRM, MRM, or PRM)
  • A proven ability to analyze complex datasets using tools like Spotfire, R, or Skyline and experience with standard instrument software such as Analyst or Xcalibur
  • In addition, the candidate should have excellent communication, presentation, and interpersonal skills, be able to work independently as well as in a team environment, and be willing and eager to learn new technologies


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

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