Scientist/Sr Scientist, Oncology Biomarker Development

South San Francisco
California, United States of America

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The Position

We seek a highly motivated Scientist/Physician Scientist to lead biomarker development efforts in support of Genentech’s pipeline in hematological malignancies. Substantial expertise in hematology, oncology, personalized healthcare approaches, and translational research is highly desirable. The individual will be responsible for designing, implementing and leading the biomarker strategy for one or more Genentech’s products. The ideal candidate will also be familiar with methodologies and platforms used for analyzing high-content NGS data with clinical outcome, deriving scientific insights and translating them into development/diagnostic opportunities. The successful candidate is expected to work seamlessly as part of a multifunctional team, have excellent oral and written communication skills, participate and contribute to team meetings, publish in high quality scientific, technical or medical journals, present at internal and external meetings.

Scope of position:

The Scientist will report to an Associate Director/Director in the Oncology Biomarker Development (OBD) within the Development Sciences Division of Genentech Research and Early Development. The individual will be responsible for the oversight of biomarker programs of one or more early and late-stage molecules. This position will be lab-enabled.

Primary responsibilities are as follows:

  • Provide exceptional scientific leadership to peers in OBD and assigned project teams (including discovery scientists, clinical researchers, bioinformatics scientists)
  • Responsible for translating preclinical hypothesis into a clinical biomarker strategies for one or more projects
  • Have deep scientific expertise of the subject and disease to champion the translation of novel scientific discoveries into clinical development opportunities or diagnostic platforms, such as detection of minimal residual disease.
  • Participate and thrive in an interactive, team oriented culture
  • Regular publication of scientific and methodological results are strongly encouraged, and scientists are expected to develop over time into externally recognized leaders in translational sciences who influence the field of personalized healthcare in oncology


  • PhD, MD or PhD/MD degree in a relevant scientific field (e.g. hematology, cancer biology, molecular biology, immunology)
  • Ability to work with large, multi-omic data sets and familiar with techniques for exploring associations of biomarkers with clinical outcomes.
  • Computational skills with statistical software packages such as R are preferred, but not essential. Experience with machine learning techniques for high dimensional data is a plus.
  • Minimum of 3 years postdoctoral basic or translational research experience in either academic and/or in an industry setting
  • Demonstrated record of cutting edge research as evidenced by first or senior authored publications in top tier journals
  • Be able to distill complex issues and clearly articulate solutions
  • Ability to collaborate, lead, influence and motivate others
  • Ability to demonstrate effectiveness and growth in a fast-paced and dynamic environment
  • Outstanding presentation and communication skills




Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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