South San Francisco
California, United States of America
We are seeking a highly motivated Scientist or Senior Scientist to join the OMNI-Biomarker Development Department within Development Sciences to drive our personalized healthcare efforts in multiple sclerosis. Our department is responsible for defining biomarker and personalized healthcare strategies, designing and implementing biomarker assays, and interpreting biomarker results. Our group uses relevant biomarkers to evaluate disease heterogeneity, target-engagement, mechanism of action, and disease modification, and to guide clinical diagnostic biomarker development. Biomarker team leaders within the department provide scientific leadership for biomarkers in clinical trials ranging from early proof-of-concept through marketed products.
The successful candidate will join our dynamic team and work to identify and assess personalized healthcare strategies in multiple sclerosis. The candidate will support our multiple sclerosis biomarker strategy, leading efforts for data analyses of internal studies and external collaborations relating to understanding clinical aspects of multiple sclerosis through genetic and other biomarker data across clinical data sets, with the opportunity for the successful Scientist to grow into a project biomarker representative/team leader. Success in these responsibilities requires a thorough understanding of disease and drug target biology, creativity and attention to detail, and experience in integrating biomarkers into clinical trials. Candidates familiar with molecular and immunological techniques including immunoassay, qPCR, whole genome sequencing methods and/or genetic analysis algorithms will be given preference. The position requires working in close partnerships across various functions including Research, Bioanalytical Assays, Diagnostics, Clinical Sciences, Biostatistics, Bioinformatics, Regulatory and with external partners. Effective communication is essential and includes presentations at cross-functional teams, internal review committees, and external conferences, and will also involve writing biomarker sections of clinical protocols, reports, regulatory filings and scientific publications.
Who You Are
Candidates must have a PhD or MD in Neurology, Neuroscience and/or Immunology, or a related field with at least 3 to 5 years of post-doctoral or fellowship experience in basic or translational research either in an academic and/or industry setting. The candidate must demonstrate a high level of independence and be able to develop hypotheses and direct analysis plans. Strong writing and communication skills are required, as evidenced by publications, meeting abstracts and/or drug development reports. We are looking for an individual who would be passionate about using their understanding of disease biology to make impactful contributions to clinical drug development. Willingness to collaborate across time zones including our Swiss site is a must. Preferred candidates will have prior experience in multiple sclerosis and a demonstrated ability to function as part of a cross-functional team such as clinical trial project teams.
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.
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