Scientist Computational Chemistry/Cheminformatics

South San Francisco
California, United States of America

Return to Search Results

The Position

Genentech is seeking a computational chemist with strong programming skills and experience in structure-based drug design, ligand-based design, and cheminformatics to join our Computer-Assisted Drug Discovery group in the Discovery Chemistry Department. 

The position entails approximately 50% applications-oriented computational chemistry and 50% software development/support, including cheminformatics and computational chemistry tool development and integration.  You will support small molecule lead discovery, optimization, and development in drug discovery projects and use your scientific programming skills to enhance our software infrastructure.

You will interact closely with interdisciplinary small molecule discovery project team members and other members of the Computational Chemistry and Cheminformatics group.  Therefore, verbal and written communication skills are a must.

You will have access to state of the art hardware, software, and infrastructure support in a fast-paced and creative environment.  Based at our beautiful South San Francisco campus, you will join our team of computational chemists, cheminformaticians, and software engineers who are committed to discovering new medicines to address unmet medical needs. This is a tremendous opportunity to do meaningful work in an exciting, dynamic environment.


Who You Are

  • Ph.D. or equivalent in Chemistry, Biochemistry, Biophysics, or related discipline
  • Experience in computational chemistry, along with a solid foundation in physical organic chemistry
  • Excellent interpersonal, verbal, and written communication skills
  • Extensive experience in scientific programming in a research environment
  • Practical, working experience with computational chemistry software from companies such as Chemical Computing Group, Dotmatics, Schrodinger, OpenEye, Cambridge Crystallographic Data Centre, and Gaussian is a plus.
  • Knowledge of data science, machine learning, and deep learning approaches is desirable
  • Industry or academic experience in small molecule drug discovery is advantageous


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

Return to Search Results