Sr./ Principal Engineer, Media Development

South San Francisco
California, United States of America

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The Position

The successful candidate will lead the Media Development group within the Cell Culture department in the Pharma Technical Development (PTD) organization. This position is based at Genentech's South San Francisco, CA site.


  • Develop chemically-defined cell culture media to meet different needs, including high-density cultures for biologics manufacturing, and cell-based therapies.
  • Innovate and apply advanced technologies to improve cell culture performance.
  • Serve as resource for state-of-the-art practice in media development.
  • Provide technical leadership and guidance to support project teams, media preparation operations, raw material assessments, and supply chain updates.
  • Lead, motivate, and develop Media Development staff.
  • Foster a lean mindset and cultivate an environment of continuous improvement.
  • Interface effectively within Cell Culture department and PTD, as well as with other internal organizations and external collaborators.
  • Exert influence inside and outside the company through presentations, publications, and participation in meetings.


We are seeking candidates with strong technical and leadership capabilities. The level of the position will depend on the qualifications of the selected candidate.

  • Bachelor's degree or higher in Life Sciences, Chemical Engineering or related discipline. PhD in Chemical Engineering highly desired.
  • 8+ years of relevant experience OR PhD with 2+ years of relevant experience. An additional 4+ years of relevant experience is required for the principal level.
  • Solid understanding of cell metabolism and tools for metabolic pathway analyses.
  • Expertise in using computational methods, metabolic models, statistical design of experiments, –omics, and other current technologies to improve cell culture processes.
  • Prior experience in media development for mammalian cell cultures.
  • Prior experience in technology transfer and development of cell-based therapies is a plus.
  • Demonstrated ability to lead and drive technical projects to completion through scientific rigor and strong organization skills.
  • Proven track record of managing and developing a highly productive and collaborative technical team.  
  • Proven track record of building and maintaining strong relationships with partners, customers, and collaborators.
  • Proven track record of excellent verbal and written communication through conference presentations and publications.


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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