Scientific Manager / Sr. Scientific Manager, Oncology Biomarker Development

South San Francisco
California, United States of America

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The Position

The Scientific or Senior Scientific Manager, OBD will lead the biomarker study planning, execution and analysis for a late clinical development program focused on Skin and Rare Cancers. The incumbent will represent OBD on molecule teams and will develop and execute the personalized healthcare (PHC) strategy for the respective therapeutics.


  • Lead biomarker strategies and plans at a single project level, provide exceptional scientific leadership to peers and the organization
  • Represent the biomarker strategy and plan for an Oncology therapeutic to the project teams, oncology biomarker review forum (OBRF), franchise teams, and late-stage portfolio committee (LSPC).
  • Lead and drive biomarker related studies and collaborations as well as data analysis and interpretation for an Oncology therapeutic
  • Lead the biomarker regulatory strategy and interaction for an Oncology therapeutic with health authorities around the globe and contribute to preparation of relevant regulatory documents
  • Oversees the biomarker strategy and plan for medical affairs sponsored activities in collaboration with the Medical affairs Biomarker Lead (MABL) and International medical Director (IMD)
  • Develop and lead biomarker collaborations with key investigators and therapeutic experts (TAEs) and thought leaders
  • Publish in high quality scientific, technical or medical journals and represent OBD externally through presentations at key internal and external meetings, advisory boards, and conferences


  • BS, MS, PhD, MD or PhD/MD degree in a relevant scientific field (e.g. pathology, molecular biology, cancer genetics, cancer biology, molecular oncology)
  • Minimum of 7-10 years’ experience in basic or translational research either in an academic and/or industry setting
  • Experience in clinical drug development and biomarkers is beneficial, including basic or advanced understanding of critical development functions, e.g. Clinical Pharmacology, Regulatory, Safety, Operations, Biostatistics, etc.
  • Experience with clinical biomarker analysis, particularly with high-dimensional data
  • Experience and understanding of diagnostic product development, particularly in Oncology would be highly desirable
  • Outstanding presentation and communication skills
  • Ability and willingness to travel and work in global time frame.


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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