Postdoctoral Research Fellow - Discovery Oncology and Discovery Chemistry

South San Francisco
California, United States of America

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The Position

We are seeking a highly talented and self-motivated Postdoctoral Research Fellow for a joint appointment in the laboratories of Ingrid Wertz and Joachim Rudolph in the Departments of Discovery Oncology and Discovery Chemistry.  The research will focus on investigating unexplored ubiquitin signaling pathways and enzymes and developing chemical probes to co-opt these for pharmacological intervention. The successful candidate will be responsible for the design and synthesis of bivalent ligand-based chemical probes and investigating them in a wide range of cellular, biochemical and molecular biology techniques. This will include the development and implementation of protein interaction assays, enzymatic assays, biophysical, and cell-based assays.  Practical experience in the area of organic chemistry and a solid understanding of molecular biology and enzymology are required, and training in the area of chemical biology is preferred.


Qualified candidates will have a Ph.D. degree with substantial experience in the areas of Organic Synthesis, Biochemistry or Chemical Biology and a demonstrated track record of success as evidenced by relevant publications in leading peer-reviewed journals.  Candidates must demonstrate outstanding communication skills, ability to operate within multidisciplinary environments, creativity, and a high degree of intellectual independence. Attention to detail and enthusiasm for science are a must.

For more information on the labs of Ingrid Wertz and Joachim Rudolph, please visit and

For more information about the postdoctoral program at Genentech please visit:

Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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