South San Francisco
California, United States of America
A postdoctoral position is available in the Department of Early Discovery Biochemistry to investigate molecular mechanisms underlying complex biology. Active areas of research include structure-function studies of protein complexes involved in cellular signaling pathways and how various post-translational modifications (e.g. ubiquitination, phosphorylation) regulate these pathways. Specific projects are ongoing in the areas of cancer biology, innate immunity and infectious disease. This position provides an opportunity to learn/apply a variety of biochemical and biophysical techniques, as well as, potential structure determination utilizing our state-of-the-art cryoEM facility. [Specifically, the facility includes two screening microscopes, Talos 200C and Glacios (to be installed in late 2019), equipped with Gatan K2 Direct Detectors, one Titan Krios with a K2 Bioquantum Direct Detector and a Titan Krios G3 (to be installed in 2020) equipped with Gatan K3 Bioquantum—plus ancillary sample preparation and vitrification equipment].
Who You Are:
Ph.D. in biochemistry, biophysics, structural biology or related discipline. Successful candidates will be highly motivated to work independently on projects with significant biological relevance in a very collaborative, multidisciplinary group. Candidates should have a strong background in protein chemistry, biophysical methods and molecular biology as evidenced by a first author paper published or accepted in a peer-reviewed journal. Strong problem solving, communication and organizational skills are highly desirable.
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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