Senior/Principal Scientist Development, Safety Assessment- Toxicology

South San Francisco
California, United States of America


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The Position

The Department of Safety Assessment at Genentech provides scientific leadership and plays an active role in the process of drug development from the discovery period through marketed products. We are seeking a Senior/Principal Scientist in Toxicology to support drug development. This role will involve working in a collaborative team environment as part of the comprehensive safety assessment of Genentech therapeutics by providing toxicology representation to programs.

Responsibilities:

The successful candidate for Senior/Principal Scientist will provide scientific leadership and play an active role in the process of drug development from discovery through marketed products, with a strong emphasis on Genentech’s small molecule development project portfolios. Working in a collaborative team environment, the Senior/Principal Scientist leads the safety assessment of Genentech therapeutics by creating a best-evidence synthesis of existing knowledge and comprehensive investigations of toxicologic activity, strategic planning, and designing/implementing/supervising toxicology studies in support of program advancement.

Responsibilities include interdisciplinary project team membership, scientific leadership in the design and implementation of safety assessment strategies to support program advancement and decision-making, preparation and review of regulatory documentation, study reports and manuscripts, representation of Genentech in meetings with regulatory authorities, investigations into mechanisms of toxicity, proactive management of potential safety liabilities and communication of impact to teams and governance committees. Experience with cross-functional teams and capability to build productive cross-functional internal and external collaborations are desired.

Additional responsibilities include mentoring of toxicologists and as needed, team members, and lead or provide support to inter- and intra-departmental initiatives.

Qualifications:

  • A PhD and post-doctorate or equivalent experience in toxicology or a relevant field along with a minimum of 8 years relevant experience in the pharmaceutical/biotechnology/CRO industry related to toxicology.
  • Extensive experience in small molecule drug development and interaction with global regulatory authorities are required.
  • Experience in developmental and reproductive toxicology is highly desirable.
  • Evidence of consistent and extensive record of impact internally and externally. 
  • Board certification in toxicology is desirable.
  • The successful candidate must also demonstrate strong decision-making, complex problem solving, critical data analysis and interpretation, excellent written and verbal communication skills; and the ability to build productive cross-functional collaborations both within and external to Genentech

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Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


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