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Postdoctoral Research Fellow - Oncology Biomarker Development, Yadav Lab

South San Francisco
California, United States of America

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The Position

A Postdoctoral Research Fellow position is available immediately in Genentech’s Oncology Biomarker Department in the group of Mahesh Yadav to work on projects related to cancer immunotherapy. 

This is unique and rare opportunity for a post-doctoral fellow with a strong computational background to work with large biomarker data sets from Roche/Genentech’s cancer immunotherapy trials to gain new mechanistic insights into neoantigen-driven immune responses in human cancers and (Yadav et al, Nature 2014, Fehlings et al, JITC 2019). The goal will be to apply these findings in improving neoantigen specific therapies and also publish findings in top tier scientific journals. The position will have plenty of opportunities to interact and collaborate with scientists in a dynamic cancer immunotherapy community at Genentech (South San Francisco campus).


  • Applicants must have a recent doctoral degree with strong computational expertise and a robust understanding in some area of biology. Preference is given for experience in immunology, oncology, genetics, or systems biology,
  • The successful applicant will have a demonstrated record of innovative scientific accomplishments as evidenced by at least one first-author paper published or accepted in a top tier journal.
  • Proficiency in programming using scripting languages (Perl/Python), R, and experience in standard bioinformatics toolkits and programs.
  • Collaborate extensively with multi-functional teams to leverage cutting-edge technologies and expertise both internally and externally. Attend and present at international meetings and author manuscripts for publications in top-tier journals.
  • Immuno-oncology PhD candidates with strong computational expertise are strongly encouraged to apply. 

What to expect from us:

  • A highly functional and collaborative research environment where we aim to translate our understanding of cancer biology to develop personalized therapies and diagnostics to transform clinical practice to benefit patient health.
  • Access to large clinical data sets and samples.
  • Access to state-of-the-art technologies and pioneering research.
  • Participation in seminar series featuring academic and industry scientists.  
  • Campus-like life style with a healthy work-life balance.
  • Mentored opportunities to further develop professional skills. 

Interested applicants should send their CV, a cover letter describing your research interests and a list of 3 references.


Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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