Postdoctoral Research Fellow, Human Genetics

South San Francisco
California, United States of America

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The Position

The McCarthy postdoc group at SSF will focus on developing and implementing analytical and experimental strategies that maximise the value of human genetics for drug discovery and precision medicine. The research will build upon work undertaken in Dr McCarthy’s academic research program at Oxford. One major area of research interest will continue to revolve around the prioritization and functional characterization of therapeutic targets -- for example, through implementing strategies for connecting regulatory variants to their downstream targets, and the high throughput perturbation of those targets in suitable cellular systems. A second strand will involve the use of global and partitioned risk scores to stratify risk, and to capture etiological and clinical heterogeneity, and the translational application of those scores. The group will continue to develop and apply these approaches in the area of metabolic disease (in part through continued interaction with academic researchers in genetic and functional consortia), but will also seek to implement analogous approaches across the wider range of diseases of interest to Genentech. 

The successful candidate will have a PhD and/or MD from a highly reputable institution, with training in either the life sciences (biology, medicine etc) or computational sciences (maths, physics, computational science, bioinformatics etc), but with proficiency and experience that spans both. We are particularly interested in candidates with strong programming skills who have existing experience of applying computational and statistical approaches to high dimensional genetic and genomic data.

As well as a strong publication record, they will have excellent communication skills, and interest in exploiting the potential of human genetics to gain fundamental insights into the biology of disease. Postdocs in our lab work in a challenging and stimulating yet supportive and interactive environment, becoming independent scientists with the ability to lead their own research groups.

For more information about the postdoc program:

Who We Are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

The next step is yours. To apply today, click on the "Apply online" button.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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