South San Francisco
California, United States of America
The McCarthy postdoc group at SSF will focus on developing and implementing analytical and experimental strategies that maximize the value of human genetics for drug discovery and precision medicine. The research will build upon work undertaken in Dr McCarthy’s academic research program at Oxford and ongoing developments at Genentech. One major area of research interest will continue to revolve around the prioritization and functional characterization of therapeutic targets -- for example, through implementing strategies for connecting regulatory variants to their downstream targets, and the high throughput perturbation of those targets in suitable cellular systems. A second strand involves the integration of high dimensional omic data (in particular proteomics) with clinical and genetic data to provide mechanistic insights into disease biology, and to identify therapeutic targets and biomarkers. The group will continue to develop and apply these approaches in the area of metabolic disease (building on existing collaborations) but will aim to implement the approaches and strategies developed across the wider range of diseases of interest to Genentech.
The successful candidate will have a PhD and/or MD from a highly reputable institution, with training in either the life sciences (biology, medicine etc) or computational sciences (maths, physics, computational science, bioinformatics etc) with proficiency and experience that spans both. They will have direct experience in applying computational and statistical approaches to high dimensional genetic and genomic data.
As well as a strong publication record, they will have excellent communication skills, and interest in exploiting the potential of human genetics to gain fundamental insights into the biology of disease. Postdocs in our lab work in a challenging and stimulating yet supportive and interactive environment, becoming independent scientists with the ability to lead their own research groups.
For more information about the Mark McCarthy's Lab at Genentech, please go to: https://www.gene.com/scientists/our-scientists/mark-mccarthy
For more information about the Postdoctoral Program at Genentech, please go to: https://www.gene.com/careers/university-and-early-career/postdocs
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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