South San Francisco
California, United States of America
The Position is placed in the BioAnalytical Sciences (BAS) Department at Genentech. We are a world-class bioanalytical center of excellence for novel strategies, technologies, and methods that enable the development of life-changing medicines. We do this by fostering an innovative and collaborative environment that values and recognizes diversity of contributions.
The BAS department is seeking a highly motivated creative Scientist to develop bioanalytical methods and strategies to support biopharmaceuticals in Genentech's Cancer Immunotherapy pipeline.
Responsibilities for this position include development and implementation of assay strategies, interpretation and reporting of immunogenicity datasets, as well as managing timelines and resources to meet project goals. The individual will work independently and in collaboration with colleagues within BAS as well as across various functional areas. The individual may also lead those collaborative groups.
Working with Scientific Researchers, this individual will be responsible for development, characterization, and qualification of in vitro methods to quantify biotherapeutic levels in various species and biological matrices, to detect and characterize immune responses evoked by the biotherapeutic, to measure biomarkers, to conduct biological characterization in support of regulatory filings, and to work with contract research organizations to transfer and validate such assays. This may involve laboratory work, the use of automation systems, as well as the use of various assay platforms, including ELISA, PCR, Quanterix, Ella, Gyros, Singulex and Luminex. Responsibilities may also include supervision of one or more Scientific Researchers. These groups will develop, optimize and qualify analytical methods in support of both in vitro and in vivo nonclinical studies as well as clinical trials. The individual will provide analytical support to programs from early development (preclinical) stages through clinical studies and regulatory filings. The successful candidate is also expected to conduct and publish novel research related to the job responsibilities.
Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring the best to the business and to their personal lives.
Who you are
In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. A Ph.D. or equivalent curriculum in immunology, Biology or a related scientific discipline is desirable and will have demonstrated relevant significant scientific ability and drug development experience. Persons without formal degree who have comparable depth and breadth of training and experience will also be considered.
Experience in an industrial setting is required, and knowledge of oncology, cancer immunotherapy is helpful. The individual should have in-depth understanding and hands-on experience in interpreting complex immunogenicity data sets, and with regulatory filings. In addition is an applicant should have experience developing quantitative analyte and anti-drug antibody assays utilizing immunoassay and/or other methodologies, along with a proven track record of solving complex bioanalytical problems.
The work will require the application of immunoassays as well as state-of-the-art assay technologies such as PCR, Quanterix, Ella, Singulex, Gyros and Luminex and other biochemical approaches. You will have experience in providing interpretation and reporting of potentially complex immunogenicity data, including assessment of its potential impact on other study parameters, including exposure, safety, and efficacy. Expertise with standard text, graphic, and presentation software is required, and familiarity with database/data archival software systems is helpful. Excellent communication, interpersonal and organizational skills are essential.
Who We Are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.
Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.
Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.
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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.
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