South San Francisco
California, United States of America
The successful candidate will be mentored by an experienced investigator with a track record of developing novel technologies that have led to multiple antibody therapeutics used to treat millions of patients worldwide. You will engineer antibodies and other proteins through rational design and molecular evolution technologies to enhance their existing properties or endow them with brand new capabilities. A major interest is to make currently intractable targets for antibodies druggable - pursuit of the ‘high-hanging fruit’. Long term research goals for the lab include intracellular delivery of protein drugs and immunogenicity risk-assessment for engineered protein therapeutics.
The qualified candidate will have a PhD in molecular biology, protein chemistry, structural biology or a related discipline. Creative individuals with a passion for science and capable of independent work in a collaborative environment are particularly encouraged to apply. Well-qualified individuals will have one or more first author research publications in high quality journals in protein/antibody engineering or a related field. Experience in protein/antibody engineering from rational design, through generation of mutants, to the expression, purification and characterization of mutant proteins is desirable. Expertise with molecular evolution technologies such as yeast or phage display is a plus. Excellent oral and written communication skills are needed.
For more information about Paul Carter’s lab at Genentech, please visit: http://www.gene.com/scientists/our-scientists/paul-carter
For more information about our Postdoctoral Program at Genentech, please visit:
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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