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Scientific Researcher / Senior Scientific Researcher, Small Molecule Automation

South San Francisco, California

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The Position

We seek an outstanding candidate to join Small Molecule Analytical Chemistry efforts within Small Molecule Pharmaceutical Sciences. Responsibilities include designing and performing high-throughput experimentation (HTE) for optimization of reaction conditions on micromole and nanomole scale. Organic chemistry reactions performed would include but not limited to palladium-catalyzed suzuki-miyaura, buchwald-hartwig, photoredox-nickel catalysis, and many others.

The successful candidate will collaborate with chemists in the discovery/medicinal chemistry department to plan and execute screening experiments and to further innovate within the field.

The successful candidate will accomplish our mission through collaboration with our subject matter experts, creative problem-solving, Design of Experiments, and use of state-of-the-art technology including robotic laboratory systems, microscopy, ultra-high-pressure LC, mass spectrometry, chiral separations, supercritical fluid chromatography (SFC) and other analytical instruments. 


  • BS/MS in a relevant scientific discipline (chemistry or chemical engineering preferred) with 2 – 5 years experience in small molecule drug discovery within the pharmaceutical industry.

  • Candidates must have good theoretical knowledge of analytical and/or organic chemistry.  

  • Some background in lab automation, chromatography (HPLC and data handling/reporting), knowledge of pharmaceutics, solid state characterization or drug discovery are desirable. 

  • Candidates should have good problem solving / communication skills, and ability to work in a collaborative team environment.  

  • The position requires good organizational skills and the ability to work well as part of a team.

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Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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