South San Francisco
California, United States of America
We are seeking a highly talented and self-motivated Postdoctoral Research Fellow to be co-mentored by Drs. Ingrid Wertz in the Departments of Discovery Oncology and Early Discovery Biochemistry at Genentech and Prof. Rachel Klevit in the Departments of Biochemistry, Pharmacology, and Chemistry at the University of Washington. The research will be conducted at Genentech and will focus on identifying and structurally characterizing endogenous substrates of wild-type and mutant BRCA1 and BARD1 tumor suppressor proteins. The successful candidate will be responsible for designing experiments and reagents to identify the binding partners, substrates, and cellular transcriptional networks regulated by wild-type and mutant BRCA1 and BARD1, and to structurally characterize the substrates.
Qualified candidates will have a Ph.D. with practical experience in molecular biology, protein purification, and structural biology along with a solid understanding of enzymology. Training or experience in the area of cell biology is preferred. The successful candidate will have demonstrated a track record of success as evidenced by relevant publications in leading peer-reviewed journals. Candidates must demonstrate outstanding communication skills, the ability to operate within multidisciplinary environments, creativity, and a high degree of intellectual independence. Attention to detail and enthusiasm for science are a must.
For more information on the labs of Ingrid Wertz and Rachel Klevit, please visit : https://www.gene.com/scientists/our-scientists/ingrid-wertz and https://www.klevitlab.org/
For more information on the postdoctoral program at Genentech please visit: https://www.gene.com/careers/university-and-early-career/postdocs
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
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