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Bioinformatics Scientist, Neuroscience Reverse Translation

South San Francisco, California

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The Position

The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Scientist to study the molecular pathways that contribute to neurological diseases including Alzheimer’s Disease and Multiple Sclerosis. Applicant will work with colleagues in Translational Genomics and Neuroscience departments to pursue novel therapeutics and biomarkers for disease areas of focus in the Neuroscience department. The applicant will lead a data-driven research program generating and leveraging high-dimensional ‘omic data from both in vitro human cell models and patient-derived tissue and biofluids.


  • Postdoctoral training, or exceptional PhD experience, in Bioinformatics, Biostatistics, Computational Biology or similar field, including familiarity and a strong desire to work in the field of Neuroscience.

  • Strong scientific publication record

  • Ability to creatively analyze and integrate high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data, CRISPR screen analysis, etc.) to generate new biological insights, and then work closely with bench scientists to develop those ideas experimentally.

  • Demonstrated competence in languages such as R or Python for bioinformatics analyses.

  • Experience thinking about the biology of neurological disease and eagerness to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease etiology.

  • Ability to work successfully as the bioinformatics lead in cross-functional teams that contribute to drug and biomarker development.

  • Excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars






Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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