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Sr Scientific Researcher, Antibody Engineering

South San Francisco, California


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The Position

The Position

We are seeking a highly talented Senior Scientific Researcher to join the Department of Antibody Engineering. The position offers the opportunity to contribute to multidisciplinary teams focused on the delivery of therapeutic molecules to Genentech’s large molecule pipeline.

This hire will focus on engineering antibodies to overcome limitations of existing medicines and design next generation biotherapeutic formats to treat cancer and other unmet medical needs. The engineering challenges will include the recruitment of unique properties to endow therapeutic molecules with novel or superior activities, achieving targeted localization, or increasing the therapeutic index. The position requires the candidate to perform hands-on laboratory science. The engineering of antibodies will be carried out through rational design or display techniques. Subsequent cell-based or SPR-based binding assays and/or functional assays will validate the successful engineering.

Who You Are

The successful candidate will have a PhD in Molecular or Cell Biology, Bioengineering, Immunology, Biochemistry, or related disciplines, or a BS/MS degree with 8+ years of research experience. Cell biology and assay experience are highly desirable. Protein engineering skills are a plus. Prior antibody engineering or drug development expertise are not essential and the position provides an excellent environment to build these skills.

A desire to independently work in a cross-functional and collaborative environment is a requirement. Excellent communication skills are a requisite, including presentation of data on project and department level. The candidate will have demonstrated the ability to learn new techniques, problem solve, and have a sustained record of productivity. Self-starters with a passion for innovation and commitment to translational science are encouraged to apply.

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Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.


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