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Neuropathologist/Scientist, Research Pathology

South San Francisco, California

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The Position

The Research Pathology Department in Genentech Research and Early Development (gRED), in association with the Department of Neuroscience is seeking an experienced neuropathologist for a Scientist / Senior Scientist / Principal Scientist position (rank equivalent to assistant / associate / full professor in academia). Candidates should have completed a residency in pathology and a fellowship in neuropathology, or have equivalent training. The successful candidate should have expertise in molecular and cellular biology using both in vitro and in vivo model systems, and possess a deep mechanistic understanding of the cellular pathways that contribute to diseases of the human nervous system (such as neurodegenerative diseases, neuroinflammation, and aging). The position will involve close collaboration with research labs in Neuroscience as well as providing pathology support for  scientists who discover and develop drugs or identify associated biomarkers for the treatment of neurological diseases. Genentech provides an exceptional research environment composed of internationally recognized scientific leaders as well as state-of-the-art facilities that provide cutting edge technologies and computational resources to support all research activities.

The Department of Research Pathology provides pathology expertise and tissue-based analysis to support basic scientific discoveries, development of drug targets, and biomarkers using both human tissues and animal models in support of drug development throughout the pipeline. Pathologists use their scientific and medical backgrounds to integrate data from sources throughout the company into a coherent analysis of human disease and animal / organoid disease models. The pathologists’ collaborative support of Genentech scientists includes histopathology interpretive expertise informed by traditional diagnostic categories, as well as by detailed and expert understanding of molecular and cellular biology. These activities are enabled by the pathology core (P-core) labs that include necropsy, clinical pathology, histopathology, immunohistochemistry / in situ hybridization, a human tissue biorepository, advanced light microscopy, electron microscopy, digital pathology, and translational tissue technologies.  The department provides high quality pathology support to laboratory and clinical scientists engaged in biomarker strategy/development/deployment across the drug development pipeline. These activities can extend into “late stage” clinical development efforts (Phase III clinical trials).


  • You have an MD or its foreign equivalent, appropriate Board Certification(s) in Pathology and Neuropathology, or Board Eligibility, and scholarly productivity in a relevant field of biomedical research.
  • A Ph.D. degree in a related field, in addition to the MD or equivalent degree, is desirable, but not required. We seek candidates who can interpret traditional diagnostic categories in the context of a detailed and current understanding of molecular, cellular, and systems neurobiology.
  • You are able to handle several projects at any given time and can distill complex issues and clearly articulate solutions.
  • You are self-motivated and you will drive to create innovative solutions to solve complex problems in a team environment.
  • You have an interest in adapting and utilizing emerging technologies in pathology.
  • You have the ability to work successfully in cross-functional teams that contribute to basic scientific discoveries, development of drug targets and biomarkers.
  • You have excellent scientific communication skills: verbally and in writing; in informal 1-1 settings, team meetings, and formal seminars. Effective communication is essential and includes presentations at cross-functional teams, internal review committees, and external conferences, and will also involve writing reports and scientific publication.
  • You have demonstrated learning agility, adaptability, collaborative skills, strong influencing skills and delivering results through teamwork.
  • You have a strong desire to contribute to our mission of translating basic science and expertise into meaningful, long-lasting benefit for patients.



Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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