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Senior Scientist, Next-Generation Biomarker Tissue Assays and Technology Development

South San Francisco
California, United States of America

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The Position

The Department of Cellular and Tissue Genomics within Genentech Research and Early Development is seeking a highly talented, creative and driven Scientist to develop next-generation biomarker tissue assays to advance biological and diagnostic discovery to advance development of innovative therapeutics and personalized health care.

The scope of activities will span biological disciplines, including immunology, molecular oncology, cancer immunology, angiogenesis, neurobiology, host-pathogen interactions and regenerative medicine and across multiple disease areas of focus in cancer, immunology, neuroscience, infectious diseases and ophthalmology.


  • Lead a basic and applied research group to discover, develop and implement development of agile research tools and diagnostics assays including, but not limited to next generation tissue profiling using multiplex spatial sequencing methods.

  • Interdisciplinary collaboration, leadership, coordination and implementation of research, engineering, and operation efforts tailored to next generation biomarker tissue assays in collaboration with Neuroscience, Molecular Oncology, Cancer Immunology, Immunology and Infectious Diseases, Pathology, Biomolecular Imaging, Biomarker Discovery, Biomarker Development, Software Engineering and data teams.

  • Development of strategies, identification, discovery and implementation of new technology offerings for biomarker tissue assays and diagnostics. Maintain knowledge in the field through new and existing collaborations with academia, technology partners and CROs on implementation of new technologies.


  • Ph.D. with relevant postdoctoral experience with both experimental and computational expertise in spatial genomics

  • Evidence of accomplishments and ability to function as an independent investigator (e.g., funding and publications as an Assistant Professor or equivalent)

  • Strong publication record of impactful discoveries that reveal novel biological pathways and/or advanced technologies to enable biological discovery

  • Proficient in bioinformatics including high throughput omics and imaging data analysis visualization, and interpretation

  • Excellent interpersonal skills with demonstrated ability to work within a team comprised of diverse expertise

  • Excellent mentoring skills across all levels

  • Excellent oral and written presentation skills

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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