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Bioinformatics Scientist/Senior Scientist, Immunology, ARDS and COVID

South San Francisco, California

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The Position

The Genentech Bioinformatics department seeks a highly motivated Reverse Translation Scientist/Senior Scientist to leverage computational biology to study the molecular pathways that contribute to acute respiratory distress syndrome (ARDS), including those associated with COVID-19. The successful candidate will work with colleagues in the Translational Genomics and Immunology departments to pursue the development of novel therapeutics and biomarkers related to ARDS. The successful candidate will work as a member of a highly collaborative team to design experiments, interpret data, and develop computational solutions to address underlying biological questions. The successful candidate will lead a computationally-driven research program focused on leveraging high-dimensional data from patient-derived tissue and biofluids to develop a better understanding of the molecular mechanisms driving ARDS.


  • You have a PhD and Postdoctoral training in Computational Biology, Biostatistics, Human Genetics, and some experience in Immunology.

  • You have evidence of scientific achievements through first or corresponding author publications in peer-reviewed scientific journals.

  • You are comfortable writing code in languages such as R, or Matlab, Python, etc. and have familiarity with UNIX and high-performance computing environments.

  • You are able to define and lead a computational research program involving the creative analysis and integration of high dimensional datasets (e.g. single cell sequence assays, genotype or WGS data, proteomics data and CRISPR screen analysis).

  • You are intensely curious about the biology of disease and eager to contribute to scientific efforts focused on understanding the molecular mechanisms underlying disease biology.

  • You have basic expertise in molecular and cellular biology.

  • You are able to work successfully as the computational lead in cross-functional teams that contribute to drug and biomarker development.

  • You have excellent scientific communication skills: verbally and in writing; with computational and non-computational audiences; in informal 1-1 settings, team meetings, and formal seminars.






Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world's most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page.

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